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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P23786 CPT2; CPT1 Carnitine O-palmitoyltransferase 2, mitochondrial (EC … Homo sapiens (Human) 658 aa

Protein Details: P23786 (CPT2)

Protein Information
Accession P23786
Protein Names Carnitine O-palmitoyltransferase 2, mitochondrial (EC 2.3.1.21) (Carnitine palmitoyltransferase II) (CPT II)
Gene Symbol CPT2; CPT1
Organism Homo sapiens (Human)
Length 658 aa
Isoforms No isoforms
Related PMIDs 29733200 31251020 32944167 33636221
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.837
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
36
LNCaP cells
Specificity: 0.837
36/46 (78.3%)
4
HAP1 cells
Specificity: 0.093
4/10 (40.0%)
2
PC3 cells
Specificity: 0.047
2/4 (50.0%)
1
Liver membrane
Specificity: 0.023
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MVPRLLLRAW11PRGPAVGPGA21PSRPLSAGSG31PGQYLQRSIV41PTMHYQDSLP
51-10051RLPIPKLEDT61IRRYLSAQKP71LLNDGQFRKT81EQFCKSFENG91IGKELHEQLV
101-150101ALDKQNKHTS111YISGPWFDMY121LSARDSVVLN131FNPFMAFNPD141PKSEYNDQLT
151-200151RATNMTVSAI161RFLKTLRAGL171LEPEVFHLNP181AKSDTITFKR191LIRFVPSSLS
201-250201WYGAYLVNAY211PLDMSQYFRL221FNSTRLPKPS231RDELFTDDKA241RHLLVLRKGN
251-300251FYIFDVLDQD261GNIVSPSEIQ271AHLKYILSDS281SPAPEFPLAY291LTSENRDIWA
301-350301ELRQKLMSSG311NEESLRKVDS321AVFCLCLDDF331PIKDLVHLSH341NMLHGDGTNR
351-400351WFDKSFNLII361AKDGSTAVHF371EHSWGDGVAV381LRFFNEVFKD391STQTPAVTPQ
401-450401SQPATTDSTV411TVQKLNFELT421DALKTGITAA431KEKFDATMKT441LTIDCVQFQR
451-500451GGKEFLKKQK461LSPDAVAQLA471FQMAFLRQYG481QTVATYESCS491TAAFKHGRTE
501-550501TIRPASVYTK511RCSEAFVREP521SRHSAGELQQ531MMVECSKYHG541QLTKEAAMGQ
551-600551GFDRHLFALR561HLAAAKGIIL571PELYLDPAYG581QINHNVLSTS591TLSSPAVNLG
601-650601GFAPVVSDGF611GVGYAVHDNW621IGCNVSSYPG631RNAREFLQCV641EKALEDMFDA
651-658651LEGKSIKS
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
84 Prediction (Medium) - -
324 Prediction (Medium) - -
326 Prediction (High) - -
445 Prediction (High) - -
639 Prediction (Low) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
215 S → C 0.002506 SNP Missense Mutation COAD
218 F → C 0.002545 SNP Missense Mutation GBM
445 C → C 0.001887 SNP Silent UCEC
497 G → C 0.001764 SNP Missense Mutation LUAD
512 C → S 0.001887 SNP Missense Mutation UCEC
620 W → C 0.002033 SNP Missense Mutation LUSC