Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P24527 | Lta4h | Leukotriene A-4 hydrolase (LTA-4 hydrolase) … | Mus musculus (Mouse) | 611 aa |
Protein Details: P24527 (Lta4h)
Protein Information
| Accession | P24527 |
|---|---|
| Protein Names | Leukotriene A-4 hydrolase (LTA-4 hydrolase) (EC 3.3.2.6) (Leukotriene A(4) hydrolase) (Tripeptide aminopeptidase LTA4H) (EC 3.4.11.4) |
| Gene Symbol | Lta4h |
| Organism | Mus musculus (Mouse) |
| Length | 611 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 29660268 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MPEVADTCSL11ASPASVCRTQ21HLHLRCSVDF31ARRTLTGTAA41LTVQSQEENL
51-10051RSLTLDTKDL61TIEKVVINGQ71EVKYTLGESQ81GYKGSPMEIS91LPIALSKNQE
101-150101IVIEISFETS111PKSSALQWLT121PEQTSGKQHP131YLFSQCQAIH141CRAILPCQDT
151-200151PSVKLTYTAE161VSVPKELVAL171MSAIRDGEAP181DPEDPSRKIY191RFNQRVPIPC
201-250201YLIALVVGAL211ESRQIGPRTL221VWSEKEQVEK231SANEFSETES241MLKIAEDLGG
251-300251PYVWGQYDLL261VLPPSFPYGG271MENPCLTFVT281PTLLAGDKSL291SNVIAHEISH
301-350301SWTGNLVTNK311TWDHFWLNEG321HTVYLERHIC331GRLFGEKFRH341FHALGGWGEL
351-400351QNTIKTFGES361HPFTKLVVDL371KDVDPDVAYS381SIPYEKGFAL391LFYLEQLLGG
401-450401PEVFLGFLKA411YVKKFSYQSV421TTDDWKSFLY431SHFKDKVDLL441NQVDWNTWLY
451-500451APGLPPVKPN461YDVTLTNACI471ALSQRWVTAK481EEDLSSFSIA491DLKDLSSHQL
501-550501NEFLAQVLQK511APLPLGHIKR521MQEVYNFNAI531NNSEIRFRWL541RLCIQSKWEE
551-600551AIPLALKMAT561EQGRMKFTRP571LFKDLAAFDK581SHDQAVHTYQ591EHKASMHPVT
601-611601AMLVGRDLKV611D
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 8 | - | - |
Brain
(35358180)
|
GPS-Palm: 0.70
Deep-Palm: 0.02
|
|
| 17 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.80
|
|
| 26 | - |
MLE
(39008777)
| - |
Deep-Palm: 0.91
|
|
| 136 | - | - | - |
GPS-Palm: 0.73
Deep-Palm: 0.17
|
|
| 141 | - | - | - |
Deep-Palm: 0.26
|
|
| 147 | SWISSPALM DBPTM CYSMODDB | Peptidase M1 N-terminal domain |
Liver
(28526873)
|
Brain
(35358180)
|
GPS-Palm: 0.83
Deep-Palm: 0.45
|
| 200 | - | - |
Brain
(35358180)
|
GPS-Palm: 0.72
Deep-Palm: 0.92
|
|
| 275 | - | - | - |
Deep-Palm: 0.89
|
|
| 330 | - | - | - |
GPS-Palm: 0.86
Deep-Palm: 0.34
|
|
| 469 | - | - | - |
Deep-Palm: 0.88
|
|
| 543 | - | - | - |
GPS-Palm: 0.88
Deep-Palm: 0.84
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
4
Liver
Specificity: 0.235
4/4 (100.0%)
2
Brain
Specificity: 0.118
2/2 (100.0%)
2
Testis
Specificity: 0.118
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
9
Brain tissue (Mass)
Specificity: 0.529
9/56 (16.1%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.