Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P24549 | Aldh1a1 | Aldehyde dehydrogenase 1A1 (EC 1.2.1.19) … | Mus musculus (Mouse) | 501 aa |
Protein Details: P24549 (Aldh1a1)
Protein Information
| Accession | P24549 |
|---|---|
| Protein Names | Aldehyde dehydrogenase 1A1 (EC 1.2.1.19) (EC 1.2.1.28) (EC 1.2.1.3) (EC 1.2.1.36) (3-deoxyglucosone dehydrogenase) (ALDH-E1) (ALHDII) (Aldehyde dehydrogenase family 1 member A1) (Aldehyde dehydrogenase, cytosolic) (Retinal dehydrogenase 1) (RALDH 1) (RalDH1) |
| Gene Symbol | Aldh1a1 |
| Organism | Mus musculus (Mouse) |
| Length | 501 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 29660268 29733200 34200797 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSSPAQPAVP11APLADLKIQH21TKIFINNEWH31NSVSGKKFPV41LNPATEEVIC
51-10051HVEEGDKADV61DKAVKAARQA71FQIGSPWRTM81DASERGRLLN91KLADLMERDR
101-150101LLLATMEALN111GGKVFANAYL121SDLGGCIKAL131KYCAGWADKI141HGQTIPSDGD
151-200151IFTYTRREPI161GVCGQIIPWN171FPMLMFIWKI181GPALSCGNTV191VVKPAEQTPL
201-250201TALHLASLIK211EAGFPPGVVN221IVPGYGPTAG231AAISSHMDVD241KVAFTGSTQV
251-300251GKLIKEAAGK261SNLKRVTLEL271GGKSPCIVFA281DADLDIAVEF291AHHGVFYHQG
301-350301QCCVAASRIF311VEESVYDEFV321KRSVERAKKY331VLGNPLTPGI341NQGPQIDKEQ
351-400351HDKILDLIES361GKKEGAKLEC371GGGRWGNKGF381FVQPTVFSNV391TDEMRIAKEE
401-450401IFGPVQQIMK411FKSVDDVIKR421ANNTTYGLAA431GLFTKDLDKA441ITVSSALQAG
451-500451VVWVNCYMML461SAQCPFGGFK471MSGNGRELGE481HGLYEYTELK491TVAMKISQKN
501-501501S
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 50 | SWISSPALM DBPTM CYSMODDB | Aldehyde dehydrogenase family Aldehyde dehydrogenase, N-terminal |
Liver
(28526873)
|
Brain
(35358180)
|
Deep-Palm: 0.98
|
| 126 | SWISSPALM DBPTM CYSMODDB | - |
Liver
(28526873)
|
Liver
(37925639)
Brain
(35358180)
|
GPS-Palm: 0.91
Deep-Palm: 0.87
|
| 133 | SWISSPALM DBPTM CYSMODDB | - |
Liver
(28526873)
| - |
GPS-Palm: 0.93
Deep-Palm: 0.86
|
| 163 | - | - | - |
GPS-Palm: 0.78
Deep-Palm: 0.16
|
|
| 186 | SWISSPALM DBPTM CYSMODDB | Aldehyde dehydrogenase family |
liver
(26165157)
Liver
(28526873)
|
Liver
(34884899)
Brain
(35358180)
Brain
(31311849)
|
GPS-Palm: 0.87
Deep-Palm: 0.92
|
| 276 | - | - | - |
GPS-Palm: 0.71
Deep-Palm: 0.98
|
|
| 302 | - | - | - |
Deep-Palm: 0.25
|
|
| 303 | - | - | - |
Deep-Palm: 0.17
|
|
| 370 | - | - | - |
GPS-Palm: 0.88
Deep-Palm: 0.98
|
|
| 456 | - | - | - |
Deep-Palm: 0.60
|
|
| 464 | - | - | - |
Deep-Palm: 0.85
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.462
6
Liver
Specificity: 0.158
6/6 (100.0%)
5
Brain
Specificity: 0.132
5/5 (100.0%)
2
Testis
Specificity: 0.053
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.840
21
Brain tissue (Mass)
Specificity: 0.553
21/56 (37.5%)
4
Liver tissue (Mass)
Specificity: 0.105
4/8 (50.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.