Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P24588 AKAP5; AKAP79 A-kinase anchor protein 5 (AKAP-5) … Homo sapiens (Human) 427 aa

Protein Details: P24588 (AKAP5)

Protein Information
Accession P24588
Protein Names A-kinase anchor protein 5 (AKAP-5) (A-kinase anchor protein 79 kDa) (AKAP 79) (H21) (cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein)
Gene Symbol AKAP5; AKAP79
Organism Homo sapiens (Human)
Length 427 aa
Isoforms No isoforms
Related PMIDs 31251020 32944167 36430497
Database Sources dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.860
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
37
LNCaP cells
Specificity: 0.860
37/46 (80.4%)
3
PC3 cells
Specificity: 0.070
3/4 (75.0%)
3
Cerebral cortex
Specificity: 0.070
3/4 (75.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501METTISEIHV11ENKDEKRSAE21GSPGAERQKE31KASMLCFKRR41KKAAKALKPK
51-10051AGSEAADVAR61KCPQEAGASD71QPEPTRGAWA81SLKRLVTRRK91RSESSKQQKP
101-150101LEGEMQPAIN111AEDADLSKKK121AKSRLKIPCI131KFPRGPKRSN141HSKIIEDSDC
151-200151SIKVQEEAEI161LDIQTQTPLN171DQATKAKSTQ181DLSEGISRKD191GDEVCESNVS
201-250201NSTTSGEKVI211SVELGLDNGH221SAIQTGTLIL231EEIETIKEKQ241DVQPQQASPL
251-300251ETSETDHQQP261VLSDVPPLPA271IPDQQIVEEA281SNSTLESAPN291GKDYESTEIV
301-350301AEETKPKDTE311LSQESDFKEN321GITEEKSKSE331ESKRMEPIAI341IITDTEISEF
351-400351DVTKSKNVPK361QFLISAENEQ371VGVFANDNGF381EDRTSEQYET391LLIETASSLV
401-427401KNAIQLSIEQ411LVNEMASDDN421KINNLLQ
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
36 DBPTM SWISSPALM Prediction (High) - -
129 DBPTM SWISSPALM Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
21 G → C 0.001887 SNP Missense Mutation UCEC
62 C → R 0.002545 SNP Missense Mutation GBM