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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P25398 RPS12 Small ribosomal subunit protein eS12 … Homo sapiens (Human) 132 aa

Protein Details: P25398 (RPS12)

Protein Information
Accession P25398
Protein Names Small ribosomal subunit protein eS12 (40S ribosomal protein S12)
Gene Symbol RPS12
Organism Homo sapiens (Human)
Length 132 aa
Isoforms No isoforms
Related PMIDs 21076176 29575903 29733200 31251020 32944167
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.375
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
12
LNCaP cells
Specificity: 0.375
12/46 (26.1%)
10
HAP1 cells
Specificity: 0.312
10/10 (100.0%)
4
293T cells
Specificity: 0.125
4/10 (40.0%)
3
PC3 cells
Specificity: 0.094
3/4 (75.0%)
2
Jurkat T cells
Specificity: 0.062
2/25 (8.0%)
1
HeLa cells
Specificity: 0.031
1/1 (100.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAEEGIAAGG11VMDVNTALQE21VLKTALIHDG31LARGIREAAK41ALDKRQAHLC
51-10051VLASNCDEPM61YVKLVEALCA71EHQINLIKVD81DNKKLGEWVG91LCKIDREGKP
101-132101RKVVGCSCVV111VKDYGKESQA121KDVIEEYFKC131KK
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
50 Prediction (Medium) - -
69 Prediction (Medium) - -
92 Prediction (High) - -
106 Experimental CYSMODDB SWISSPALM DBPTM Prediction (High) - 29575903
108 Experimental CYSMODDB SWISSPALM DBPTM Prediction (Medium) - 29575903
130 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
61 Y → C 0.002427 SNP Missense Mutation BLCA
? ? → ? 0.002294 SNP Nonstop Mutation OV