Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P25446 Fas Tumor necrosis factor receptor superfamily … Mus musculus (Mouse) 327 aa

Protein Details: P25446 (Fas)

Protein Information
AccessionP25446
Protein NamesTumor necrosis factor receptor superfamily member 6 (Apo-1 antigen) (Apoptosis-mediating surface antigen FAS) (FASLG receptor) (CD antigen CD95)
Gene SymbolFas
OrganismMus musculus (Mouse)
Length327 aa
IsoformsNo isoforms
Related PMIDs 37925639
Database SourcesdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MLWIWAVLPL11VLAGSQLRVH21TQGTNSISES31LKLRRRVRET41DKNCSEGLYQ
51-10051GGPFCCQPCQ61PGKKKVEDCK71MNGGTPTCAP81CTEGKEYMDK91NHYADKCRRC
101-150101TLCDEEHGLE111VETNCTLTQN121TKCKCKPDFY131CDSPGCEHCV141RCASCEHGTL
151-200151EPCTATSNTN161CRKQSPRNRL171WLLTILVLLI181PLVFIYRKYR191KRKCWKRRQD
201-250201DPESRTSSRE211TIPMNASNLS221LSKYIPRIAE231DMTIQEAKKF241ARENNIKEGK
251-300251IDEIMHDSIQ261DTAEQKVQLL271LCWYQSHGKS281DAYQDLIKGL291KKAECRRTLD
301-327301KFQDMVQKDL311GKSTPDTGNE321NEGQCLE
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
44 - - -
GPS-Palm: 0.68
Deep-Palm: 0.56
55 - - -
GPS-Palm: 0.86
Deep-Palm: 0.07
56 - - -
GPS-Palm: 0.90
Deep-Palm: 0.06
59 - - -
GPS-Palm: 0.86
Deep-Palm: 0.06
69 - - -
Deep-Palm: 0.04
78 - - -
Deep-Palm: 0.04
81 - - -
Deep-Palm: 0.03
97 - - -
Deep-Palm: 0.06
100 - - -
Deep-Palm: 0.03
103 - - -
Deep-Palm: 0.05
115 - - -
Deep-Palm: 0.05
123 - - -
Deep-Palm: 0.04
125 - - -
Deep-Palm: 0.03
131 - - -
Deep-Palm: 0.04
136 - - -
Deep-Palm: 0.03
139 - - -
Deep-Palm: 0.03
142 - - -
Deep-Palm: 0.03
145 - - -
Deep-Palm: 0.03
153 - - -
Deep-Palm: 0.06
161 - - -
Deep-Palm: 0.39
194 DBPTM SWISSPALM - - -
GPS-Palm: 0.78
Deep-Palm: 0.92
272 - - -
GPS-Palm: 0.65
Deep-Palm: 0.80
295 - - -
GPS-Palm: 0.84
Deep-Palm: 0.94
325 - - -
GPS-Palm: 0.93
Deep-Palm: 0.02
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
Liver
Specificity: 1.000
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine