Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P25911 Lyn Tyrosine-protein kinase Lyn (EC 2.7.10.2) … Mus musculus (Mouse) 512 aa

Protein Details: P25911 (Lyn)

Protein Information
AccessionP25911
Protein NamesTyrosine-protein kinase Lyn (EC 2.7.10.2) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene SymbolLyn
OrganismMus musculus (Mouse)
Length512 aa
IsoformsNo isoforms
Related PMIDs 28526873 29575903 29733200 31772009 34884899 37925639
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MGCIKSKRKD11NLNDDEVDSK21TQPVRNTDRT31IYVRDPTSNK41QQRPVPEFHL
51-10051LPGQRFQTKD61PEEQGDIVVA71LYPYDGIHPD81DLSFKKGEKM91KVLEEHGEWW
101-150101KAKSLSSKRE111GFIPSNYVAK121VNTLETEEWF131FKDITRKDAE141RQLLAPGNSA
151-200151GAFLIRESET161LKGSFSLSVR171DYDPMHGDVI181KHYKIRSLDN191GGYYISPRIT
201-250201FPCISDMIKH211YQKQSDGLCR221RLEKACISPK231PQKPWDKDAW241EIPRESIKLV
251-300251KKLGAGQFGE261VWMGYYNNST271KVAVKTLKPG281TMSVQAFLEE291ANLMKTLQHD
301-350301KLVRLYAVVT311KEEPIYIITE321FMAKGSLLDF331LKSDEGGKVL341LPKLIDFSAQ
351-400351IAEGMAYIER361KNYIHRDLRA371ANVLVSESLM381CKIADFGLAR391VIEDNEYTAR
401-450401EGAKFPIKWT411APEAINFGCF421TIKSDVWSFG431ILLYEIVTYG441KIPYPGRTNA
451-500451DVMSALSQGY461RMPRMENCPD471ELYDIMKMCW481KEKAEERPTF491DYLQSVLDDF
501-512501YTATEGQYQQ511QP
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
3 - - -
GPS-Palm: 0.97
Deep-Palm: 0.02
203 SWISSPALM DBPTM CYSMODDB SH2 domain
Liver (28526873)
-
GPS-Palm: 0.90
Deep-Palm: 0.27
219 - - -
GPS-Palm: 0.78
Deep-Palm: 0.85
226 - - -
GPS-Palm: 0.93
Deep-Palm: 0.89
381 - - -
Deep-Palm: 0.95
419 SWISSPALM DBPTM CYSMODDB Protein tyrosine and serine/threonine kinase
Liver (28526873)
-
GPS-Palm: 0.90
Deep-Palm: 0.15
468 - - -
Deep-Palm: 0.04
479 - - -
Deep-Palm: 0.02
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.545
6
Liver
Specificity: 0.545
6/6 (100.0%)
3
Raw 264.7
Specificity: 0.273
3/3 (100.0%)
1
Brain
Specificity: 0.091
1/1 (100.0%)
1
NSC
Specificity: 0.091
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine