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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P26150 Hsd3b3 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type … Mus musculus (Mouse) 373 aa

Protein Details: P26150 (Hsd3b3)

Protein Information
AccessionP26150
Protein Names3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 3 (3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type III) (3-beta-HSD III) [Includes: 3-beta-hydroxy-Delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid Delta-isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)]
Gene SymbolHsd3b3
OrganismMus musculus (Mouse)
Length373 aa
IsoformsNo isoforms
Related PMIDs 28526873 34884899 37925639
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MPGWSCLVTG11AGGFLGQRII21QLLVQEKDLE31EIRVLDKVFK41PETREQFFNL
51-10051GTSIKVTVLE61GDILDTQYLR71RACQGISVVI81HTAAIIDVTG91VIPRQTILDV
101-150101NLKGTQNLLE111ACIQASVPAF121IFSSSVDVAG131PNSYKDIVLN141GHEDEHREST
151-200151WSDPYPYSKK161MAEKAVLAAN171GSMLKNGGTL181QTCALRPMCI191YGERSQFLSN
201-250201TIIKALKNKF211ILRGGGKFST221ANPVYVGNVA231WAHILAARGL241RNPKKSPNIQ
251-300251GEFYYISDDT261PHQSYDDLNY271TLSKEWGFCL281NSRWYLPVPI291LYWLAFLLET
301-350301VSFLLSPIYR311YIPPFNRHLV321TLTASTFTFS331YKKAQRDLGY341EPLVSWEEAK
351-373351QKTSEWIGTL361VEQHRETLDT371KSQ
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
6 NAD(P)-binding domain superfamily - -
Deep-Palm: 0.05
73 - - -
Deep-Palm: 0.89
112 - - -
Deep-Palm: 0.92
183 - - -
Deep-Palm: 0.83
189 - - -
Deep-Palm: 0.83
279 SWISSPALM DBPTM CYSMODDB 3-beta hydroxysteroid dehydrogenase/isomerase family
Liver (28526873)
-
Deep-Palm: 0.42
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
6
Liver
Specificity: 1.000
6/6 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine