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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P26678 PLN Phospholamban (PLB) Homo sapiens (Human) 52 aa

Protein Details: P26678 (PLN)

Protein Information
AccessionP26678
Protein NamesPhospholamban (PLB)
Gene SymbolPLN
OrganismHomo sapiens (Human)
Length52 aa
IsoformsNo isoforms
Related PMIDs 33636221
Database SourcesPTMDSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MEKVQYLTRS11AIRRASTIEM21PQQARQKLQN31LFINFCLILI41CLLLICIIVM
51-5251LL
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
36 PTMD Phospholamban - -
GPS-Palm: 0.81
Deep-Palm: 0.41
41 - - -
Deep-Palm: 0.03
46 - - -
GPS-Palm: 0.70
Deep-Palm: 0.02
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
heart
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
25 R → C 0.001887 SNP Missense Mutation UCEC