Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P26842 | CD27 | CD27 antigen (CD27L receptor) (T-cell … | Homo sapiens (Human) | 260 aa |
Protein Details: P26842 (CD27)
Protein Information
| Accession | P26842 |
|---|---|
| Protein Names | CD27 antigen (CD27L receptor) (T-cell activation antigen CD27) (T14) (Tumor necrosis factor receptor superfamily member 7) (CD antigen CD27) |
| Gene Symbol | CD27 |
| Organism | Homo sapiens (Human) |
| Length | 260 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26111759 |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MARPHPWWLC11VLGTLVGLSA21TPAPKSCPER31HYWAQGKLCC41QMCEPGTFLV
51-10051KDCDQHRKAA61QCDPCIPGVS71FSPDHHTRPH81CESCRHCNSG91LLVRNCTITA
101-150101NAECACRNGW111QCRDKECTEC121DPLPNPSLTA131RSSQALSPHP141QPTHLPYVSE
151-200151MLEARTAGHM161QTLADFRQLP171ARTLSTHWPP181QRSLCSSDFI191RILVIFSGMF
201-250201LVFTLAGALF211LHQRRKYRSN221KGESPVEPAE231PCHYSCPREE241EGSTIPIQED
251-260251YRKPEPACSP
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 10 | Tumour necrosis factor receptor 7 CD27 antigen receptor | - | - |
GPS-Palm: 0.69
Deep-Palm: 0.09
|
|
| 27 | Tumor Necrosis Factor Receptor, subunit A, domain 2 TNF receptor-like CD27 antigen receptor | - | - |
Deep-Palm: 0.85
|
|
| 39 | TNFR/NGFR cysteine-rich region TNF receptor-like CD27 antigen receptor Tumor Necrosis Factor Receptor, subunit A, domain 2 | - | - |
Deep-Palm: 0.07
|
|
| 40 | Tumor Necrosis Factor Receptor, subunit A, domain 2 TNF receptor-like CD27 antigen receptor TNFR/NGFR cysteine-rich region | - | - |
Deep-Palm: 0.05
|
|
| 43 | TNF receptor-like CD27 antigen receptor Tumor Necrosis Factor Receptor, subunit A, domain 2 TNFR/NGFR cysteine-rich region | - | - |
GPS-Palm: 0.77
Deep-Palm: 0.07
|
|
| 53 | - | - | - |
GPS-Palm: 0.72
Deep-Palm: 0.04
|
|
| 62 | - | - | - |
Deep-Palm: 0.07
|
|
| 65 | - | - | - |
Deep-Palm: 0.06
|
|
| 81 | - | - | - |
Deep-Palm: 0.07
|
|
| 84 | - | - | - |
Deep-Palm: 0.06
|
|
| 87 | - | - | - |
Deep-Palm: 0.05
|
|
| 96 | - | - | - |
Deep-Palm: 0.04
|
|
| 104 | - | - | - |
Deep-Palm: 0.12
|
|
| 106 | - | - | - |
Deep-Palm: 0.04
|
|
| 112 | - | - | - |
Deep-Palm: 0.03
|
|
| 117 | - | - | - |
Deep-Palm: 0.10
|
|
| 120 | - | - | - |
Deep-Palm: 0.32
|
|
| 185 | - | - | - |
Deep-Palm: 0.78
|
|
| 232 | - | - | - |
Deep-Palm: 0.42
|
|
| 236 | - | - | - |
Deep-Palm: 0.24
|
|
| 258 | - | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.02
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
Primary T cell
Specificity: 1.000
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 197 | S → C | 0.002427 | SNP | Missense Mutation | BLCA |