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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P27144 AK4; AK3; AK3L1 Adenylate kinase 4, mitochondrial (EC … Homo sapiens (Human) 223 aa

Protein Details: P27144 (AK4)

Protein Information
Accession P27144
Protein Names Adenylate kinase 4, mitochondrial (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase 3-like) (GTP:AMP phosphotransferase AK4)
Gene Symbol AK4; AK3; AK3L1
Organism Homo sapiens (Human)
Length 223 aa
Isoforms No isoforms
Related PMIDs 31251020 33636221
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.963
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
26
LNCaP cells
Specificity: 0.963
26/46 (56.5%)
1
Liver membrane
Specificity: 0.037
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MASKLLRAVI11LGPPGSGKGT21VCQRIAQNFG31LQHLSSGHFL41RENIKASTEV
51-10051GEMAKQYIEK61SLLVPDHVIT71RLMMSELENR81RGQHWLLDGF91PRTLGQAEAL
101-150101DKICEVDLVI111SLNIPFETLK121DRLSRRWIHP131PSGRVYNLDF141NPPHVHGIDD
151-200151VTGEPLVQQE161DDKPEAVAAR171LRQYKDVAKP181VIELYKSRGV191LHQFSGTETN
201-223201KIWPYVYTLF211SNKITPIQSK221EAY
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
22 Prediction (Medium) - -
104 Prediction (Low) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
104 C → Y 0.001887 SNP Missense Mutation UCEC
124 R → C 0.001887 SNP Missense Mutation UCEC