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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P27348 YWHAQ 14-3-3 protein theta (14-3-3 protein … Homo sapiens (Human) 245 aa

Protein Details: P27348 (YWHAQ)

Protein Information
Accession P27348
Protein Names 14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene Symbol YWHAQ
Organism Homo sapiens (Human)
Length 245 aa
Isoforms No isoforms
Related PMIDs 19801377 21076176 29733200 31251020 32944167 36430497
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.293
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
12
LNCaP cells
Specificity: 0.293
12/46 (26.1%)
10
HAP1 cells
Specificity: 0.244
10/10 (100.0%)
6
Jurkat T cells
Specificity: 0.146
6/25 (24.0%)
4
PC3 cells
Specificity: 0.098
4/4 (100.0%)
4
293T cells
Specificity: 0.098
4/10 (40.0%)
4
Cerebral cortex
Specificity: 0.098
4/4 (100.0%)
1
DU145 cells
Specificity: 0.024
1/2 (50.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MEKTELIQKA11KLAEQAERYD21DMATCMKAVT31EQGAELSNEE41RNLLSVAYKN
51-10051VVGGRRSAWR61VISSIEQKTD71TSDKKLQLIK81DYREKVESEL91RSICTTVLEL
101-150101LDKYLIANAT111NPESKVFYLK121MKGDYFRYLA131EVACGDDRKQ141TIDNSQGAYQ
151-200151EAFDISKKEM161QPTHPIRLGL171ALNFSVFYYE181ILNNPELACT191LAKTAFDEAI
201-245201AELDTLNEDS211YKDSTLIMQL221LRDNLTLWTS231DSAGEECDAA241EGAEN
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
25 Prediction (Low) - -
94 Prediction (High) - -
134 Prediction (Medium) - -
189 Prediction (Medium) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
19 Y → C 0.012195 SNP Missense Mutation MESO
125 Y → C 0.002506 SNP Missense Mutation COAD
139 K → _Q140insLACGDDRK 0.002427 INS In Frame Ins BLCA
139 K → _Q140insLACGDDRK 0.002033 INS In Frame Ins LUSC
167 R → C 0.002288 SNP Missense Mutation STAD