Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P27773 | Pdia3 | Protein disulfide-isomerase A3 (EC 5.3.4.1) … | Mus musculus (Mouse) | 505 aa |
Protein Details: P27773 (Pdia3)
Protein Information
| Accession | P27773 |
|---|---|
| Protein Names | Protein disulfide-isomerase A3 (EC 5.3.4.1) (58 kDa glucose-regulated protein) (58 kDa microsomal protein) (p58) (Disulfide isomerase ER-60) (Endoplasmic reticulum resident protein 57) (ER protein 57) (ERp57) (Endoplasmic reticulum resident protein 60) (ER protein 60) (ERp60) |
| Gene Symbol | Pdia3 |
| Organism | Mus musculus (Mouse) |
| Length | 505 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 29217618 29660268 29733200 34200797 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MRFSCLALLP11GVALLLASAR21LAAASDVLEL31TDENFESRVS41DTGSAGLMLV
51-10051EFFAPWCGHC61KRLAPEYEAA71ATRLKGIVPL81AKVDCTANTN91TCNKYGVSGY
101-150101PTLKIFRDGE111EAGAYDGPRT121ADGIVSHLKK131QAGPASVPLR141TEEEFKKFIS
151-200151DKDASVVGFF161RDLFSDGHSE171FLKAASNLRD181NYRFAHTNIE191SLVKEYDDNG
201-250201EGITIFRPLH211LANKFEDKTV221AYTEKKMTSG231KIKKFIQDSI241FGLCPHMTED
251-300251NKDLIQGKDL261LTAYYDVDYE271KNAKGSNYWR281NRVMMVAKKF291LDAGHKLNFA
301-350301VASRKTFSHE311LSDFGLESTT321GEVPVVAIRT331AKGEKFVMQE341EFSRDGKALE
351-400351QFLQEYFDGN361LKRYLKSEPI371PESNEGPVKV381VVAENFDDIV391NEEDKDVLIE
401-450401FYAPWCGHCK411NLEPKYKELG421EKLSKDPNIV431IAKMDATAND441VPSPYEVKGF
451-500451PTIYFSPANK461KLTPKKYEGG471RELNDFISYL481QREATNPPII491QEEKPKKKKK
501-505501AQEDL
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 5 | - | - | - |
GPS-Palm: 0.93
Deep-Palm: 0.13
|
|
| 57 | - | - | - |
GPS-Palm: 0.85
Deep-Palm: 0.69
|
|
| 60 | - | - | - |
Deep-Palm: 0.88
|
|
| 85 | Thioredoxin |
MLE
(39008777)
|
Brain
(35358180)
|
GPS-Palm: 0.76
Deep-Palm: 0.97
|
|
| 92 | - |
MLE
(39008777)
|
Brain
(35358180)
|
Deep-Palm: 0.86
|
|
| 244 | SWISSPALM DBPTM CYSMODDB | - |
Liver
(28526873)
liver
(26165157)
|
Liver
(34884899)
Brain
(35358180)
|
GPS-Palm: 0.76
Deep-Palm: 0.71
|
| 406 | - | - | - |
Deep-Palm: 0.61
|
|
| 409 | - | - | - |
Deep-Palm: 0.87
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.429
6
Liver
Specificity: 0.128
6/6 (100.0%)
5
Brain
Specificity: 0.106
5/5 (100.0%)
2
Testis
Specificity: 0.043
2/2 (100.0%)
1
Raw 264.7
Specificity: 0.021
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
33
Brain tissue (Mass)
Specificity: 0.702
33/56 (58.9%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.