Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P28474 Adh5 Alcohol dehydrogenase class-3 (EC 1.1.1.1) … Mus musculus (Mouse) 374 aa

Protein Details: P28474 (Adh5)

Protein Information
AccessionP28474
Protein NamesAlcohol dehydrogenase class-3 (EC 1.1.1.1) (Alcohol dehydrogenase 2) (Alcohol dehydrogenase 5) (Alcohol dehydrogenase B2) (ADH-B2) (Alcohol dehydrogenase class-III) (Glutathione-dependent formaldehyde dehydrogenase) (FALDH) (FDH) (GSH-FDH) (EC 1.1.1.-) (S-(hydroxymethyl)glutathione dehydrogenase) (EC 1.1.1.284)
Gene SymbolAdh5
OrganismMus musculus (Mouse)
Length374 aa
IsoformsNo isoforms
Related PMIDs 28526873 29733200 34200797 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MANQVIRCKA11AVAWEAGKPL21SIEEIEVAPP31KAHEVRIKIL41ATAVCHTDAY
51-10051TLSGADPEGC61FPVILGHEGA71GIVESVGEGV81TKLKAGDTVI91PLYIPQCGEC
101-150101KFCLNPKTNL111CQKIRVTQGK121GLMPDGTSRF131TCKGKSVFHF141MGTSTFSEYT
151-200151VVADISVAKI161DPSAPLDKVC171LLGCGISTGY181GAAVNTAKVE191PGSTCAVFGL
201-250201GGVGLAVIMG211CKVAGASRII221GIDINKDKFA231KAKEFGASEC241ISPQDFSKSI
251-300251QEVLVEMTDG261GVDYSFECIG271NVKVMRSALE281AAHKGWGVSV291VVGVAASGEE
301-350301ISTRPFQLVT311GRTWKGTAFG321GWKSVESVPK331LVSEYMSKKI341KVDEFVTGNL
351-374351SFDQINQAFD361LMHSGDSIRT371VLKM
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
8 GroES-like superfamily - -
GPS-Palm: 0.88
Deep-Palm: 0.07
45 Alcohol dehydrogenase-like, N-terminal ALCOHOL DEHYDROGENASE GroES-like superfamily - -
GPS-Palm: 0.80
Deep-Palm: 0.93
60 - - -
Deep-Palm: 0.80
97 Alcohol dehydrogenase GroES-like domain
Brain (34200797)
Brain (35358180)
Deep-Palm: 0.94
100 Alcohol dehydrogenase GroES-like domain
Brain (34200797)
Brain (35358180)
GPS-Palm: 0.71
Deep-Palm: 0.52
103 -
Brain (34200797)
-
Deep-Palm: 0.29
111 - - -
GPS-Palm: 0.90
Deep-Palm: 0.60
132 - - -
Deep-Palm: 0.73
170 - -
Brain (35358180)
GPS-Palm: 0.73
Deep-Palm: 0.98
174 - -
Brain (35358180)
GPS-Palm: 0.86
Deep-Palm: 0.98
195 - -
Brain (35358180)
Deep-Palm: 0.97
211 - -
Brain (35358180)
GPS-Palm: 0.90
Deep-Palm: 0.97
240 SWISSPALM DBPTM CYSMODDB Zinc-binding dehydrogenase
Liver (28526873)
Brain (35358180)
GPS-Palm: 0.86
Deep-Palm: 0.96
268 - -
Brain (35358180)
GPS-Palm: 0.77
Deep-Palm: 0.91
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.455
5
Liver
Specificity: 0.185
5/5 (100.0%)
4
Brain
Specificity: 0.148
4/4 (100.0%)
2
Testis
Specificity: 0.074
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
16
Brain tissue (Mass)
Specificity: 0.593
16/56 (28.6%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine