Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P29966 | MARCKS; MACS; PRKCSL | Myristoylated alanine-rich C-kinase substrate (MARCKS) … | Homo sapiens (Human) | 332 aa |
Protein Details: P29966 (MARCKS)
Protein Information
| Accession | P29966 |
|---|---|
| Protein Names | Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (80K-L protein) (PKCSL) |
| Gene Symbol | MARCKS; MACS; PRKCSL |
| Organism | Homo sapiens (Human) |
| Length | 332 aa |
| Isoforms | No isoforms |
| Related PMIDs | 22496122 25914232 29733200 31251020 32944167 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.333
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
12
LNCaP cells
Specificity: 0.333
12/46 (26.1%)
6
HAP1 cells
Specificity: 0.167
6/10 (60.0%)
6
293T cells
Specificity: 0.167
6/10 (60.0%)
4
PC3 cells
Specificity: 0.111
4/4 (100.0%)
4
Cerebral cortex
Specificity: 0.111
4/4 (100.0%)
3
CEMx174 cells
Specificity: 0.083
3/3 (100.0%)
1
Endothelial cells
Specificity: 0.028
1/2 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MGAQFSKTAA11KGEAAAERPG21EAAVASSPSK31ANGQENGHVK41VNGDASPAAA
51-10051ESGAKEELQA61NGSAPAADKE71EPAAAGSGAA81SPSAAEKGEP91AAAAAPEAGA
101-150101SPVEKEAPAE111GEAAEPGSPT121AAEGEAASAA131SSTSSPKAED141GATPSPSNET
151-200151PKKKKKRFSF161KKSFKLSGFS171FKKNKKEAGE181GGEAEAPAAE191GGKDEAAGGA
201-250201AAAAAEAGAA211SGEQAAAPGE221EAAAGEEGAA231GGDPQEAKPQ241EAAVAPEKPP
251-300251ASDETKAAEE261PSKVEEKKAE271EAGASAAACE281APSAAGPGAP291PEQEAAPAEE
301-332301PAAAAASSAC311AAPSQEAQPE321CSPEAPPAEA331AE
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 279 | Prediction (Low) | - | - |
| 310 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 167 | S → C | 0.002033 | SNP | Missense Mutation | LUSC |