Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P30041 | PRDX6; AOP2; KIAA0106 | Peroxiredoxin-6 (EC 1.11.1.27) (1-Cys peroxiredoxin) … | Homo sapiens (Human) | 224 aa |
Protein Details: P30041 (PRDX6)
Protein Information
| Accession | P30041 |
|---|---|
| Protein Names | Peroxiredoxin-6 (EC 1.11.1.27) (1-Cys peroxiredoxin) (1-Cys PRX) (24 kDa protein) (Acidic calcium-independent phospholipase A2) (aiPLA2) (EC 3.1.1.4) (Antioxidant protein 2) (Glutathione-dependent peroxiredoxin) (Liver 2D page spot 40) (Lysophosphatidylcholine acyltransferase 5) (LPC acyltransferase 5) (LPCAT-5) (Lyso-PC acyltransferase 5) (EC 2.3.1.23) (Non-selenium glutathione peroxidase) (NSGPx) (Red blood cells page spot 12) |
| Gene Symbol | PRDX6; AOP2; KIAA0106 |
| Organism | Homo sapiens (Human) |
| Length | 224 aa |
| Isoforms | No isoforms |
| Related PMIDs | 22496122 24357059 29733200 31251020 31382980 32944167 33636221 36430497 |
| Database Sources | PTMD |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.444
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
12
LNCaP cells
Specificity: 0.444
12/46 (26.1%)
4
293T cells
Specificity: 0.148
4/10 (40.0%)
4
Cerebral cortex
Specificity: 0.148
4/4 (100.0%)
3
PC3 cells
Specificity: 0.111
3/4 (75.0%)
2
Endothelial cells
Specificity: 0.074
2/2 (100.0%)
1
U937 cells
Specificity: 0.037
1/1 (100.0%)
1
Liver membrane
Specificity: 0.037
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MPGGLLLGDV11APNFEANTTV21GRIRFHDFLG31DSWGILFSHP41RDFTPVCTTE
51-10051LGRAAKLAPE61FAKRNVKLIA71LSIDSVEDHL81AWSKDINAYN91CEEPTEKLPF
101-150101PIIDDRNREL111AILLGMLDPA121EKDEKGMPVT131ARVVFVFGPD141KKLKLSILYP
151-200151ATTGRNFDEI161LRVVISLQLT171AEKRVATPVD181WKDGDSVMVL191PTIPEEEAKK
201-224201LFPKGVFTKE211LPSGKKYLRY221TPQP
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 47 | PTMD Prediction (High) | AhpC/TSA family | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 24 | R → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 132 | R → C | 0.002506 | SNP | Missense Mutation | COAD |