Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P30408 | TM4SF1 | Transmembrane 4 L6 family member … | Homo sapiens (Human) | 202 aa |
Protein Details: P30408 (TM4SF1)
Protein Information
| Accession | P30408 |
|---|---|
| Protein Names | Transmembrane 4 L6 family member 1 (Membrane component chromosome 3 surface marker 1) (Tumor-associated antigen L6) |
| Gene Symbol | TM4SF1 |
| Organism | Homo sapiens (Human) |
| Length | 202 aa |
| Isoforms | No isoforms |
| Related PMIDs | 24357059 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MCYGKCARCI11GHSLVGLALL21CIAANILLYF31PNGETKYASE41NHLSRFVWFF
51-10051SGIVGGGLLM61LLPAFVFIGL71EQDDCCGCCG81HENCGKRCAM91LSSVLAALIG
101-150101IAGSGYCVIV111AALGLAEGPL121CLDSLGQWNY131TFASTEGQYL141LDTSTWSECT
151-200151EPKHIVEWNV161SLFSILLALG171GIEFILCLIQ181VINGVLGGIC191GFCCSHQQQY
201-202201DC
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 2 | - | - | - |
Deep-Palm: 0.01
|
|
| 6 | SWISSPALM DBPTM CYSMODDB | L6 membrane protein |
HeLa
(29575903)
| - |
Deep-Palm: 0.02
|
| 9 | SWISSPALM DBPTM CYSMODDB | L6 membrane protein |
HeLa
(29575903)
| - |
Deep-Palm: 0.04
|
| 21 | - | - | - |
Deep-Palm: 0.94
|
|
| 75 | - | - | - |
Deep-Palm: 0.12
|
|
| 76 | - | - | - |
Deep-Palm: 0.40
|
|
| 78 | - | - | - |
Deep-Palm: 0.08
|
|
| 79 | - | - | - |
Deep-Palm: 0.11
|
|
| 84 | - | - | - |
Deep-Palm: 0.40
|
|
| 88 | - | - | - |
Deep-Palm: 0.67
|
|
| 107 | SWISSPALM DBPTM CYSMODDB | L6 membrane protein | - | - |
Deep-Palm: 0.97
|
| 121 | SWISSPALM DBPTM CYSMODDB | L6 membrane protein |
HeLa
(29575903)
| - |
Deep-Palm: 0.96
|
| 149 | SWISSPALM DBPTM CYSMODDB | L6 membrane protein |
HeLa
(29575903)
| - |
Deep-Palm: 0.45
|
| 177 | - | - | - |
Deep-Palm: 0.97
|
|
| 190 | - | - | - |
Deep-Palm: 0.02
|
|
| 193 | SWISSPALM DBPTM CYSMODDB | - |
HeLa
(29575903)
| - |
Deep-Palm: 0.01
|
| 194 | SWISSPALM DBPTM CYSMODDB | - |
HeLa
(29575903)
| - |
Deep-Palm: 0.01
|
| 202 | SWISSPALM DBPTM CYSMODDB | - | - | - |
Deep-Palm: 0.01
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
HUVECs
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 21 | C → F | 0.002506 | SNP | Missense Mutation | COAD |
| 21 | C → S | 0.002294 | SNP | Missense Mutation | OV |
| 29 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 77 | G → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 84 | C → G | 0.001764 | SNP | Missense Mutation | LUAD |
| 84 | C → Wfs*39 | 0.004219 | DEL | Frame Shift Del | SARC |
| 107 | C → S | 0.001764 | SNP | Missense Mutation | LUAD |
| ? | ? → ? | 0.001887 | SNP | Missense Mutation | UCEC |