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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P30408 TM4SF1; M3S1; TAAL6 Transmembrane 4 L6 family member … Homo sapiens (Human) 202 aa

Protein Details: P30408 (TM4SF1)

Protein Information
Accession P30408
Protein Names Transmembrane 4 L6 family member 1 (Membrane component chromosome 3 surface marker 1) (Tumor-associated antigen L6)
Gene Symbol TM4SF1; M3S1; TAAL6
Organism Homo sapiens (Human)
Length 202 aa
Isoforms No isoforms
Related PMIDs 24357059 29575903 32944167
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
2
PC3 cells
Specificity: 0.667
2/4 (50.0%)
1
Endothelial cells
Specificity: 0.333
1/2 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MCYGKCARCI11GHSLVGLALL21CIAANILLYF31PNGETKYASE41NHLSRFVWFF
51-10051SGIVGGGLLM61LLPAFVFIGL71EQDDCCGCCG81HENCGKRCAM91LSSVLAALIG
101-150101IAGSGYCVIV111AALGLAEGPL121CLDSLGQWNY131TFASTEGQYL141LDTSTWSECT
151-200151EPKHIVEWNV161SLFSILLALG171GIEFILCLIQ181VINGVLGGIC191GFCCSHQQQY
201-202201DC
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
2 Prediction (High) - -
6 Experimental CYSMODDB SWISSPALM DBPTM Prediction (Medium) L6 membrane protein 29575903
9 Experimental CYSMODDB SWISSPALM DBPTM L6 membrane protein 29575903
78 Prediction (Low) - -
107 CYSMODDB SWISSPALM DBPTM Prediction (Low) L6 membrane protein -
121 Experimental CYSMODDB SWISSPALM DBPTM L6 membrane protein 29575903
149 Experimental CYSMODDB SWISSPALM DBPTM L6 membrane protein 29575903
190 Prediction (Low) - -
193 Experimental CYSMODDB SWISSPALM DBPTM - 29575903
194 Experimental CYSMODDB SWISSPALM DBPTM - 29575903
202 CYSMODDB SWISSPALM DBPTM Prediction (Medium) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
21 C → F 0.002506 SNP Missense Mutation COAD
21 C → S 0.002294 SNP Missense Mutation OV
29 Y → C 0.001887 SNP Missense Mutation UCEC
77 G → C 0.001887 SNP Missense Mutation UCEC
84 C → G 0.001764 SNP Missense Mutation LUAD
84 C → Wfs*39 0.004219 DEL Frame Shift Del SARC
107 C → S 0.001764 SNP Missense Mutation LUAD
? ? → ? 0.001887 SNP Missense Mutation UCEC