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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P30679 GNA15 Guanine nucleotide-binding protein subunit alpha-15 … Homo sapiens (Human) 374 aa

Protein Details: P30679 (GNA15)

Protein Information
AccessionP30679
Protein NamesGuanine nucleotide-binding protein subunit alpha-15 (G alpha-15) (G-protein subunit alpha-15) (Epididymis tissue protein Li 17E) (Guanine nucleotide-binding protein subunit alpha-16) (G alpha-16) (G-protein subunit alpha-16)
Gene SymbolGNA15
OrganismHomo sapiens (Human)
Length374 aa
IsoformsNo isoforms
Related PMIDs 19137006 24357059 26111759 31382980
Database SourcesdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MARSLTWRCC11PWCLTEDEKA21AARVDQEINR31ILLEQKKQDR41GELKLLLLGP
51-10051GESGKSTFIK61QMRIIHGAGY71SEEERKGFRP81LVYQNIFVSM91RAMIEAMERL
101-150101QIPFSRPESK111HHASLVMSQD121PYKVTTFEKR131YAAAMQWLWR141DAGIRACYER
151-200151RREFHLLDSA161VYYLSHLERI171TEEGYVPTAQ181DVLRSRMPTT191GINEYCFSVQ
201-250201KTNLRIVDVG211GQKSERKKWI221HCFENVIALI231YLASLSEYDQ241CLEENNQENR
251-300251MKESLALFGT261ILELPWFKST271SVILFLNKTD281ILEEKIPTSH291LATYFPSFQG
301-350301PKQDAEAAKR311FILDMYTRMY321TGCVDGPEGS331KKGARSRRLF341SHYTCATDTQ
351-374351NIRKVFKDVR361DSVLARYLDE371INLL
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
9 DBPTM SWISSPALM - - -
Deep-Palm: 0.03
10 DBPTM SWISSPALM - - -
Deep-Palm: 0.02
13 - - -
Deep-Palm: 0.12
147 - - -
Deep-Palm: 0.86
196 - - -
Deep-Palm: 0.92
222 - - -
Deep-Palm: 0.90
241 - - -
Deep-Palm: 0.82
323 - - -
Deep-Palm: 0.87
345 - - -
Deep-Palm: 0.89
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.714
5
Jurkat T cell
Specificity: 0.714
5/5 (100.0%)
1
U937 cell
Specificity: 0.143
1/1 (100.0%)
1
HUVECs
Specificity: 0.143
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
130 R → C 0.001887 SNP Missense Mutation UCEC
139 W → C 0.002427 SNP Missense Mutation BLCA
150 R → C 0.007299 SNP Missense Mutation READ
353 R → C 0.002288 SNP Missense Mutation STAD