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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P30825 SLC7A1; ATRC1; ERR; REC1L High affinity cationic amino acid … Homo sapiens (Human) 629 aa

Protein Details: P30825 (SLC7A1)

Protein Information
Accession P30825
Protein Names High affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (Ecotropic retroviral leukemia receptor homolog) (Ecotropic retrovirus receptor homolog) (Solute carrier family 7 member 1) (System Y+ basic amino acid transporter)
Gene Symbol SLC7A1; ATRC1; ERR; REC1L
Organism Homo sapiens (Human)
Length 629 aa
Isoforms No isoforms
Related PMIDs 19137006 19801377 26111759 29575903 29733200 31251020 32651440 32944167
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.639
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
39
LNCaP cells
Specificity: 0.639
39/46 (84.8%)
12
Jurkat T cells
Specificity: 0.197
12/25 (48.0%)
4
HAP1 cells
Specificity: 0.066
4/10 (40.0%)
3
PC3 cells
Specificity: 0.049
3/4 (75.0%)
2
DU145 cells
Specificity: 0.033
2/2 (100.0%)
1
HeLa cells
Specificity: 0.016
1/1 (100.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MGCKVLLNIG11QQMLRRKVVD21CSREETRLSR31CLNTFDLVAL41GVGSTLGAGV
51-10051YVLAGAVARE61NAGPAIVISF71LIAALASVLA81GLCYGEFGAR91VPKTGSAYLY
101-150101SYVTVGELWA111FITGWNLILS121YIIGTSSVAR131AWSATFDELI141GRPIGEFSRT
151-200151HMTLNAPGVL161AENPDIFAVI171IILILTGLLT181LGVKESAMVN191KIFTCINVLV
201-250201LGFIMVSGFV211KGSVKNWQLT221EEDFGNTSGR231LCLNNDTKEG241KPGVGGFMPF
251-300251GFSGVLSGAA261TCFYAFVGFD271CIATTGEEVK281NPQKAIPVGI291VASLLICFIA
301-350301YFGVSAALTL311MMPYFCLDNN321SPLPDAFKHV331GWEGAKYAVA341VGSLCALSAS
351-400351LLGSMFPMPR361VIYAMAEDGL371LFKFLANVND381RTKTPIIATL391ASGAVAAVMA
401-450401FLFDLKDLVD411LMSIGTLLAY421SLVAACVLVL431RYQPEQPNLV441YQMASTSDEL
451-500451DPADQNELAS461TNDSQLGFLP471EAEMFSLKTI481LSPKNMEPSK491ISGLIVNIST
501-550501SLIAVLIITF511CIVTVLGREA521LTKGALWAVF531LLAGSALLCA541VVTGVIWRQP
551-600551ESKTKLSFKV561PFLPVLPILS571IFVNVYLMMQ581LDQGTWVRFA591VWMLIGFIIY
601-629601FGYGLWHSEE611ASLDADQART621PDGNLDQCK
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
3 Experimental CYSMODDB SWISSPALM DBPTM Prediction (High) - 29575903, 19801377
21 Prediction (Medium) - -
31 Prediction (Low) - -
83 Prediction (Medium) - -
232 Prediction (Low) - -
345 Prediction (Medium) - -
426 Prediction (High) - -
511 Prediction (High) - -
539 Prediction (Medium) - -
628 Experimental Prediction (High) - 29575903
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
59 R → C 0.001887 SNP Missense Mutation UCEC
232 C → G 0.002294 SNP Missense Mutation OV
302 F → C 0.002427 SNP Missense Mutation BLCA
501 S → C 0.001764 SNP Missense Mutation LUAD