Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P30837 | ALDH1B1 | Aldehyde dehydrogenase X, mitochondrial (EC … | Homo sapiens (Human) | 517 aa |
Protein Details: P30837 (ALDH1B1)
Protein Information
| Accession | P30837 |
|---|---|
| Protein Names | Aldehyde dehydrogenase X, mitochondrial (EC 1.2.1.3) (Aldehyde dehydrogenase 5) (Aldehyde dehydrogenase family 1 member B1) |
| Gene Symbol | ALDH1B1 |
| Organism | Homo sapiens (Human) |
| Length | 517 aa |
| Isoforms | No isoforms |
| Related PMIDs | 24357059 29733200 31251020 31382980 32651440 33636221 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MLRFLAPRLL11SLQGRTARYS21SAAALPSPIL31NPDIPYNQLF41INNEWQDAVS
51-10051KKTFPTVNPT61TGEVIGHVAE71GDRADVDRAV81KAAREAFRLG91SPWRRMDASE
101-150101RGRLLNRLAD111LVERDRVYLA121SLETLDNGKP131FQESYALDLD141EVIKVYRYFA
151-200151GWADKWHGKT161IPMDGQHFCF171TRHEPVGVCG181QIIPWNFPLV191MQGWKLAPAL
201-250201ATGNTVVMKV211AEQTPLSALY221LASLIKEAGF231PPGVVNIITG241YGPTAGAAIA
251-300251QHVDVDKVAF261TGSTEVGHLI271QKAAGDSNLK281RVTLELGGKS291PSIVLADADM
301-350301EHAVEQCHEA311LFFNMGQCCC321AGSRTFVEES331IYNEFLERTV341EKAKQRKVGN
351-400351PFELDTQQGP361QVDKEQFERV371LGYIQLGQKE381GAKLLCGGER391FGERGFFIKP
401-450401TVFGGVQDDM411RIAKEEIFGP421VQPLFKFKKI431EEVVERANNT441RYGLAAAVFT
451-500451RDLDKAMYFT461QALQAGTVWV471NTYNIVTCHT481PFGGFKESGN491GRELGEDGLK
501-517501AYTEVKTVTI511KVPQKNS
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 169 | - | - | - |
Deep-Palm: 0.23
|
|
| 179 | - | - | - |
GPS-Palm: 0.73
Deep-Palm: 0.22
|
|
| 307 | - | - | - |
Deep-Palm: 0.22
|
|
| 318 | - | - | - |
GPS-Palm: 0.70
Deep-Palm: 0.12
|
|
| 319 | - | - | - |
GPS-Palm: 0.88
Deep-Palm: 0.10
|
|
| 320 | - | - | - |
GPS-Palm: 0.84
Deep-Palm: 0.10
|
|
| 386 | - | - | - |
GPS-Palm: 0.92
Deep-Palm: 0.97
|
|
| 478 | - | - | - |
Deep-Palm: 0.72
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.400
4
LNCaP
Specificity: 0.364
4/4 (100.0%)
1
HAP1 cell
Specificity: 0.091
1/1 (100.0%)
1
U937 cell
Specificity: 0.091
1/1 (100.0%)
1
Jurkat T cell
Specificity: 0.091
1/1 (100.0%)
1
293T cell
Specificity: 0.091
1/1 (100.0%)
1
heart
Specificity: 0.091
1/1 (100.0%)
1
HUVECs
Specificity: 0.091
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
LNCaP cells (Mass)
Specificity: 0.091
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 19 | Y → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 88 | R → C | 0.003559 | SNP | Missense Mutation | KIRP |
| 107 | R → C | 0.001969 | SNP | Missense Mutation | LGG |
| 418 | F → C | 0.001969 | SNP | Missense Mutation | LGG |