Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P30837 | ALDH1B1; ALDH5; ALDHX | Aldehyde dehydrogenase X, mitochondrial (EC … | Homo sapiens (Human) | 517 aa |
Protein Details: P30837 (ALDH1B1)
Protein Information
| Accession | P30837 |
|---|---|
| Protein Names | Aldehyde dehydrogenase X, mitochondrial (EC 1.2.1.3) (Aldehyde dehydrogenase 5) (Aldehyde dehydrogenase family 1 member B1) |
| Gene Symbol | ALDH1B1; ALDH5; ALDHX |
| Organism | Homo sapiens (Human) |
| Length | 517 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 24357059 29733200 31251020 31382980 32651440 32944167 33636221 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.673
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
37
LNCaP cells
Specificity: 0.673
37/46 (80.4%)
6
HAP1 cells
Specificity: 0.109
6/10 (60.0%)
4
293T cells
Specificity: 0.073
4/10 (40.0%)
2
DU145 cells
Specificity: 0.036
2/2 (100.0%)
2
PC3 cells
Specificity: 0.036
2/4 (50.0%)
1
Jurkat T cells
Specificity: 0.018
1/25 (4.0%)
1
U937 cells
Specificity: 0.018
1/1 (100.0%)
1
Endothelial cells
Specificity: 0.018
1/2 (50.0%)
1
Liver membrane
Specificity: 0.018
1/1 (100.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MLRFLAPRLL11SLQGRTARYS21SAAALPSPIL31NPDIPYNQLF41INNEWQDAVS
51-10051KKTFPTVNPT61TGEVIGHVAE71GDRADVDRAV81KAAREAFRLG91SPWRRMDASE
101-150101RGRLLNRLAD111LVERDRVYLA121SLETLDNGKP131FQESYALDLD141EVIKVYRYFA
151-200151GWADKWHGKT161IPMDGQHFCF171TRHEPVGVCG181QIIPWNFPLV191MQGWKLAPAL
201-250201ATGNTVVMKV211AEQTPLSALY221LASLIKEAGF231PPGVVNIITG241YGPTAGAAIA
251-300251QHVDVDKVAF261TGSTEVGHLI271QKAAGDSNLK281RVTLELGGKS291PSIVLADADM
301-350301EHAVEQCHEA311LFFNMGQCCC321AGSRTFVEES331IYNEFLERTV341EKAKQRKVGN
351-400351PFELDTQQGP361QVDKEQFERV371LGYIQLGQKE381GAKLLCGGER391FGERGFFIKP
401-450401TVFGGVQDDM411RIAKEEIFGP421VQPLFKFKKI431EEVVERANNT441RYGLAAAVFT
451-500451RDLDKAMYFT461QALQAGTVWV471NTYNIVTCHT481PFGGFKESGN491GRELGEDGLK
501-517501AYTEVKTVTI511KVPQKNS
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 179 | Prediction (Low) | - | - |
| 318 | Prediction (Low) | - | - |
| 319 | Prediction (Medium) | - | - |
| 320 | Prediction (Medium) | - | - |
| 386 | Prediction (High) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 19 | Y → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 88 | R → C | 0.003559 | SNP | Missense Mutation | KIRP |
| 107 | R → C | 0.001969 | SNP | Missense Mutation | LGG |
| 418 | F → C | 0.001969 | SNP | Missense Mutation | LGG |