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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P30989 NTSR1 Neurotensin receptor type 1 (NT-R-1) … Homo sapiens (Human) 418 aa

Protein Details: P30989 (NTSR1)

Protein Information
AccessionP30989
Protein NamesNeurotensin receptor type 1 (NT-R-1) (NTR1) (High-affinity levocabastine-insensitive neurotensin receptor) (NTRH)
Gene SymbolNTSR1
OrganismHomo sapiens (Human)
Length418 aa
IsoformsNo isoforms
Related PMIDs 32944167
Database SourcesdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MRLNSSAPGT11PGTPAADPFQ21RAQAGLEEAL31LAPGFGNASG41NASERVLAAP
51-10051SSELDVNTDI61YSKVLVTAVY71LALFVVGTVG81NTVTAFTLAR91KKSLQSLQST
101-150101VHYHLGSLAL111SDLLTLLLAM121PVELYNFIWV131HHPWAFGDAG141CRGYYFLRDA
151-200151CTYATALNVA161SLSVERYLAI171CHPFKAKTLM181SRSRTKKFIS191AIWLASALLA
201-250201VPMLFTMGEQ211NRSADGQHAG221GLVCTPTIHT231ATVKVVIQVN241TFMSFIFPMV
251-300251VISVLNTIIA261NKLTVMVRQA271AEQGQVCTVG281GEHSTFSMAI291EPGRVQALRH
301-350301GVRVLRAVVI311AFVVCWLPYH321VRRLMFCYIS331DEQWTPFLYD341FYHYFYMVTN
351-400351ALFYVSSTIN361PILYNLVSAN371FRHIFLATLA381CLCPVWRRRR391KRPAFSRKAD
401-418401SVSSNHTLSS411NATRETLY
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
141 - - -
Deep-Palm: 0.07
151 - - -
Deep-Palm: 0.71
171 - - -
GPS-Palm: 0.85
Deep-Palm: 0.96
224 - - -
Deep-Palm: 0.68
277 - - -
Deep-Palm: 0.73
315 - - -
GPS-Palm: 0.92
Deep-Palm: 0.34
327 - - -
GPS-Palm: 0.70
Deep-Palm: 0.03
381 DBPTM SWISSPALM - - -
GPS-Palm: 0.97
Deep-Palm: 0.97
383 DBPTM SWISSPALM - - -
GPS-Palm: 0.97
Deep-Palm: 0.95
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
PC3
Specificity: 1.000
4/4 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
140 G → C 0.004219 SNP Missense Mutation SARC
141 C → C 0.001887 SNP Silent UCEC
142 R → C 0.002545 SNP Missense Mutation GBM
142 R → C 0.002141 SNP Missense Mutation SKCM
142 R → C 0.015152 SNP Missense Mutation KICH
148 R → C 0.001014 SNP Missense Mutation BRCA
148 R → C 0.002288 SNP Missense Mutation STAD
148 R → C 0.002506 SNP Missense Mutation COAD
166 R → C 0.002506 SNP Missense Mutation COAD
166 R → C 0.001887 SNP Missense Mutation UCEC
268 R → C 0.001969 SNP Missense Mutation HNSC
268 R → C 0.003460 SNP Missense Mutation CESC
277 C → F 0.002294 SNP Missense Mutation OV
301 G → C 0.001764 SNP Missense Mutation LUAD
303 R → C 0.002288 SNP Missense Mutation STAD
303 R → C 0.001887 SNP Missense Mutation UCEC
381 C → W 0.002288 SNP Missense Mutation STAD
383 C → R 0.002506 SNP Missense Mutation COAD
414 R → C 0.002141 SNP Missense Mutation SKCM
151* C → ? 0.002033 SNP Nonsense Mutation LUSC