Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P31648 | Slc6a1 | Sodium- and chloride-dependent GABA transporter … | Mus musculus (Mouse) | 599 aa |
Protein Details: P31648 (Slc6a1)
Protein Information
| Accession | P31648 |
|---|---|
| Protein Names | Sodium- and chloride-dependent GABA transporter 1 (GAT-1) (Solute carrier family 6 member 1) |
| Gene Symbol | Slc6a1 |
| Organism | Mus musculus (Mouse) |
| Length | 599 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 35358180 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MATDNSKVAD11GQISTEVSEA21PVASDKPKTL31VVKVQKKAGD41LPDRDTWKGR
51-10051FDFLMSCVGY61AIGLGNVWRF71PYLCGKNGGG81AFLIPYFLTL91IFAGVPLFLL
101-150101ECSLGQYTSI111GGLGVWKLAP121MFKGVGLAAA131VLSFWLNIYY141IVIISWAIYY
151-200151LYNSFTTTLP161WKQCDNPWNT171DRCFSNYSLV181NTTNMTSAVV191EFWERNMHQM
201-250201TDGLDKPGQI211RWPLAITLAI221AWVLVYFCIW231KGVGWTGKVV241YFSATYPYIM
251-300251LIILFFRGVT261LPGAKEGILF271YITPNFRKLS281DSEVWLDAAT291QIFFSYGLGL
301-350301GSLIALGSYN311SFHNNVYRDS321IIVCCINSCT331SMFAGFVIFS341IVGFMAHVTK
351-400351RSIADVAASG361PGLAFLAYPE371AVTQLPISPL381WAILFFSMLL391MLGIDSQFCT
401-450401VEGFITALVD411EYPRLLRNRR421ELFIAAVCIV431SYLIGLSNIT441QGGIYVFKLF
451-500451DYYSASGMSL461LFLVFFECVS471ISWFYGVNRF481YDNIQEMVGS491RPCIWWKLCW
501-550501SFFTPIIVAG511VFLFSAVQMT521PLTMGSYVFP531KWGQGVGWLM541ALSSMVLIPG
551-599551YMAYMFLTLK561GSLKQRLQVM571IQPSEDIVRP581ENGPEQPQAG591SSASKEAYI
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 57 | - | - | - |
GPS-Palm: 0.84
Deep-Palm: 0.72
|
|
| 74 | - | - |
Brain
(35358180)
|
GPS-Palm: 0.87
Deep-Palm: 0.96
|
|
| 102 | - | - | - |
Deep-Palm: 0.97
|
|
| 164 | SWISSPALM DBPTM CYSMODDB | Sodium:neurotransmitter symporter family |
Forebrain
(28680068)
|
Brain
(35358180)
|
Deep-Palm: 0.05
|
| 173 | - | - | - |
Deep-Palm: 0.08
|
|
| 228 | - | - | - |
GPS-Palm: 0.84
Deep-Palm: 0.89
|
|
| 324 | - | - | - |
GPS-Palm: 0.81
Deep-Palm: 0.02
|
|
| 325 | - | - | - |
GPS-Palm: 0.73
Deep-Palm: 0.02
|
|
| 329 | - | - | - |
Deep-Palm: 0.02
|
|
| 399 | - | - | - |
GPS-Palm: 0.68
Deep-Palm: 0.15
|
|
| 428 | - | - | - |
GPS-Palm: 0.86
Deep-Palm: 0.95
|
|
| 468 | - | - | - |
Deep-Palm: 0.09
|
|
| 493 | SWISSPALM DBPTM CYSMODDB | Sodium:neurotransmitter symporter family |
Forebrain
(28680068)
| - |
Deep-Palm: 0.14
|
| 499 | - | - | - |
Deep-Palm: 0.38
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
Brain
Specificity: 0.057
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
33
Brain tissue (Mass)
Specificity: 0.943
33/56 (58.9%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.