Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P31937 | HIBADH | 3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH) (EC … | Homo sapiens (Human) | 336 aa |
Protein Details: P31937 (HIBADH)
Protein Information
| Accession | P31937 |
|---|---|
| Protein Names | 3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH) (EC 1.1.1.31) |
| Gene Symbol | HIBADH |
| Organism | Homo sapiens (Human) |
| Length | 336 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.962
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
25
LNCaP cells
Specificity: 0.962
25/46 (54.3%)
1
Cerebral cortex
Specificity: 0.038
1/4 (25.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAASLRLLGA11ASGLRYWSRR21LRPAAGSFAA31VCSRSVASKT41PVGFIGLGNM
51-10051GNPMAKNLMK61HGYPLIIYDV71FPDACKEFQD81AGEQVVSSPA91DVAEKADRII
101-150101TMLPTSINAI111EAYSGANGIL121KKVKKGSLLI131DSSTIDPAVS141KELAKEVEKM
151-200151GAVFMDAPVS161GGVGAARSGN171LTFMVGGVED181EFAAAQELLG191CMGSNVVYCG
201-250201AVGTGQAAKI211CNNMLLAISM221IGTAEAMNLG231IRLGLDPKLL241AKILNMSSGR
251-300251CWSSDTYNPV261PGVMDGVPSA271NNYQGGFGTT281LMAKDLGLAQ291DSATSTKSPI
301-336301LLGSLAHQIY311RMMCAKGYSK321KDFSSVFQFL331REEETF
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 32 | Prediction (High) | - | - |
| 191 | Prediction (Low) | - | - |
| 211 | Prediction (High) | - | - |
| 251 | Prediction (Low) | - | - |
| 314 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 182 | F → C | 0.017544 | SNP | Missense Mutation | UCS |
| 314 | C → F | 0.001764 | SNP | Missense Mutation | LUAD |