Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P31943 HNRNPH1; HNRPH; HNRPH1 Heterogeneous nuclear ribonucleoprotein H (hnRNP … Homo sapiens (Human) 449 aa

Protein Details: P31943 (HNRNPH1)

Protein Information
Accession P31943
Protein Names Heterogeneous nuclear ribonucleoprotein H (hnRNP H) [Cleaved into: Heterogeneous nuclear ribonucleoprotein H, N-terminally processed]
Gene Symbol HNRNPH1; HNRPH; HNRPH1
Organism Homo sapiens (Human)
Length 449 aa
Isoforms No isoforms
Related PMIDs 21076176 29575903 29733200 31251020 32944167 36430497
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.590
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
36
LNCaP cells
Specificity: 0.590
36/46 (78.3%)
10
HAP1 cells
Specificity: 0.164
10/10 (100.0%)
4
Jurkat T cells
Specificity: 0.066
4/25 (16.0%)
4
PC3 cells
Specificity: 0.066
4/4 (100.0%)
4
293T cells
Specificity: 0.066
4/10 (40.0%)
2
Cerebral cortex
Specificity: 0.033
2/4 (50.0%)
1
HeLa cells
Specificity: 0.016
1/1 (100.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MMLGTEGGEG11FVVKVRGLPW21SCSADEVQRF31FSDCKIQNGA41QGIRFIYTRE
51-10051GRPSGEAFVE61LESEDEVKLA71LKKDRETMGH81RYVEVFKSNN91VEMDWVLKHT
101-150101GPNSPDTAND111GFVRLRGLPF121GCSKEEIVQF131FSGLEIVPNG141ITLPVDFQGR
151-200151STGEAFVQFA161SQEIAEKALK171KHKERIGHRY181IEIFKSSRAE191VRTHYDPPRK
201-250201LMAMQRPGPY211DRPGAGRGYN221SIGRGAGFER231MRRGAYGGGY241GGYDDYNGYN
251-300251DGYGFGSDRF261GRDLNYCFSG271MSDHRYGDGG281STFQSTTGHC291VHMRGLPYRA
301-350301TENDIYNFFS311PLNPVRVHIE321IGPDGRVTGE331ADVEFATHED341AVAAMSKDKA
351-400351NMQHRYVELF361LNSTAGASGG371AYEHRYVELF381LNSTAGASGG391AYGSQMMGGM
401-449401GLSNQSSYGG411PASQQLSGGY421GGGYGGQSSM431SGYDQVLQEN441SSDFQSNIA
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
22 CYSMODDB SWISSPALM DBPTM Prediction (Medium) - -
34 Prediction (Low) - -
122 Prediction (High) - -
267 Prediction (Low) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
17 G → C 0.001887 SNP Missense Mutation UCEC
22 C → Y 0.001764 SNP Missense Mutation LUAD
51 G → C 0.001969 SNP Missense Mutation HNSC
210 Y → C 0.001887 SNP Missense Mutation UCEC
329 G → C 0.002294 SNP Missense Mutation OV
388 S → C 0.002033 SNP Missense Mutation LUSC