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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P31943 HNRNPH1 Heterogeneous nuclear ribonucleoprotein H (hnRNP … Homo sapiens (Human) 449 aa

Protein Details: P31943 (HNRNPH1)

Protein Information
AccessionP31943
Protein NamesHeterogeneous nuclear ribonucleoprotein H (hnRNP H) [Cleaved into: Heterogeneous nuclear ribonucleoprotein H, N-terminally processed]
Gene SymbolHNRNPH1
OrganismHomo sapiens (Human)
Length449 aa
IsoformsNo isoforms
Related PMIDs 29575903 29733200 31251020 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MMLGTEGGEG11FVVKVRGLPW21SCSADEVQRF31FSDCKIQNGA41QGIRFIYTRE
51-10051GRPSGEAFVE61LESEDEVKLA71LKKDRETMGH81RYVEVFKSNN91VEMDWVLKHT
101-150101GPNSPDTAND111GFVRLRGLPF121GCSKEEIVQF131FSGLEIVPNG141ITLPVDFQGR
151-200151STGEAFVQFA161SQEIAEKALK171KHKERIGHRY181IEIFKSSRAE191VRTHYDPPRK
201-250201LMAMQRPGPY211DRPGAGRGYN221SIGRGAGFER231MRRGAYGGGY241GGYDDYNGYN
251-300251DGYGFGSDRF261GRDLNYCFSG271MSDHRYGDGG281STFQSTTGHC291VHMRGLPYRA
301-350301TENDIYNFFS311PLNPVRVHIE321IGPDGRVTGE331ADVEFATHED341AVAAMSKDKA
351-400351NMQHRYVELF361LNSTAGASGG371AYEHRYVELF381LNSTAGASGG391AYGSQMMGGM
401-449401GLSNQSSYGG411PASQQLSGGY421GGGYGGQSSM431SGYDQVLQEN441SSDFQSNIA
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
22 SWISSPALM DBPTM CYSMODDB Nucleotide-binding alpha-beta plait domain superfamily RNA-binding domain superfamily
SW480 cell line (26865113)
cerebral cortex (36430497)
GPS-Palm: 0.87
Deep-Palm: 0.86
34 RNA-binding domain superfamily Epithelial Splicing Regulatory Nucleotide-binding alpha-beta plait domain superfamily - -
GPS-Palm: 0.76
Deep-Palm: 0.18
122 - - -
GPS-Palm: 0.94
Deep-Palm: 0.96
267 - - -
GPS-Palm: 0.66
Deep-Palm: 0.32
290 - - -
Deep-Palm: 0.33
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.333
3
LNCaP
Specificity: 0.273
3/3 (100.0%)
2
HAP1 cell
Specificity: 0.182
2/2 (100.0%)
2
cerebral cortex
Specificity: 0.182
2/2 (100.0%)
1
HeLa cell
Specificity: 0.091
1/1 (100.0%)
1
293T cell
Specificity: 0.091
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
Cerebral Cortex (Mass)
Specificity: 0.182
2/4 (50.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
17 G → C 0.001887 SNP Missense Mutation UCEC
22 C → Y 0.001764 SNP Missense Mutation LUAD
51 G → C 0.001969 SNP Missense Mutation HNSC
210 Y → C 0.001887 SNP Missense Mutation UCEC
329 G → C 0.002294 SNP Missense Mutation OV
388 S → C 0.002033 SNP Missense Mutation LUSC