Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P31946-2 | YWHAB | 14-3-3 protein beta/alpha (Protein 1054) … | Homo sapiens (Human) | 244 aa |
Protein Details: P31946-2 (YWHAB)
Protein Information
| Accession | P31946-2 |
|---|---|
| Protein Names | 14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed] |
| Gene Symbol | YWHAB |
| Organism | Homo sapiens (Human) |
| Length | 244 aa |
| Isoforms | |
| Related PMIDs | 32944167 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MDKSELVQKA11KLAEQAERYD21DMAAAMKAVT31EQGHELSNEE41RNLLSVAYKN
51-10051VVGARRSSWR61VISSIEQKTE71RNEKKQQMGK81EYREKIEAEL91QDICNDVLEL
101-150101LDKYLIPNAT111QPESKVFYLK121MKGDYFRYLS131EVASGDNKQT141TVSNSQQAYQ
151-200151EAFEISKKEM161QPTHPIRLGL171ALNFSVFYYE181ILNSPEKACS191LAKTAFDEAI
201-244201AELDTLNEES211YKDSTLIMQL221LRDNLTLWTS231ENQGDEGDAG241EGEN
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 96 | - | - | - |
Deep-Palm: 0.95
|
|
| 191 | - | - | - |
Deep-Palm: 0.91
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
4
PC3
Specificity: 0.500
4/4 (100.0%)
4
cerebral cortex
Specificity: 0.500
4/4 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 57 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 62 | R → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 85 | R → C | 0.003460 | SNP | Missense Mutation | CESC |
| 169 | R → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 169 | R → C | 0.005660 | SNP | Missense Mutation | UCEC |