Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P31947-2 | SFN | 14-3-3 protein sigma (Epithelial cell … | Homo sapiens (Human) | 216 aa |
Protein Details: P31947-2 (SFN)
Protein Information
| Accession | P31947-2 |
|---|---|
| Protein Names | 14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin) |
| Gene Symbol | SFN |
| Organism | Homo sapiens (Human) |
| Length | 216 aa |
| Isoforms | |
| Related PMIDs | 31251020 32944167 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MERASLIQKA11KLAEQAERYE21DMAAFMKGAV31EKGEELSCEE41RNLLSVAYKN
51-10051VVGGQRAAWR61VLSSIEQKSN71EEGSEEKGPE81VREYRVFYLK91MKGDYYRYLA
101-150101EVATGDDKKR111IIDSARSAYQ121EAMDISKKEM131PPTNPIRLGL141ALNFSVFHYE
151-200151IANSPEEAIS161LAKTTFDEAM171ADLHTLSEDS181YKDSTLIMQL191LRDNLTLWTA
201-216201DNAGEEGGEA211PQEPQS
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 38 | 14-3-3 domain superfamily 14-3-3 domain 14-3-3 protein 14-3-3 protein, conserved site | - | - |
Deep-Palm: 0.98
|
|
| 96 | - | - | - |
Deep-Palm: 0.98
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
4
PC3
Specificity: 0.667
4/4 (100.0%)
1
LNCaP
Specificity: 0.167
1/1 (100.0%)
1
cerebral cortex
Specificity: 0.167
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 59 | W → C | 0.003460 | SNP | Missense Mutation | CESC |