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UniProt ID Gene Symbol Protein Name Organism Length Action
P32241 VIPR1 Vasoactive intestinal polypeptide receptor 1 … Homo sapiens (Human) 457 aa

Protein Details: P32241 (VIPR1)

Protein Information
AccessionP32241
Protein NamesVasoactive intestinal polypeptide receptor 1 (VIP-R-1) (Pituitary adenylate cyclase-activating polypeptide type II receptor) (PACAP type II receptor) (PACAP-R-2) (PACAP-R2) (VPAC1 receptor) (VPAC1R)
Gene SymbolVIPR1
OrganismHomo sapiens (Human)
Length457 aa
IsoformsNo isoforms
Related PMIDs No related PMIDs
Database SourcesdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MRPPSPLPAR11WLCVLAGALA21WALGPAGGQA31ARLQEECDYV41QMIEVQHKQC
51-10051LEEAQLENET61IGCSKMWDNL71TCWPATPRGQ81VVVLACPLIF91KLFSSIQGRN
101-150101VSRSCTDEGW111THLEPGPYPI121ACGLDDKAAS131LDEQQTMFYG141SVKTGYTIGY
151-200151GLSLATLLVA161TAILSLFRKL171HCTRNYIHMH181LFISFILRAA191AVFIKDLALF
201-250201DSGESDQCSE211GSVGCKAAMV221FFQYCVMANF231FWLLVEGLYL241YTLLAVSFFS
251-300251ERKYFWGYIL261IGWGVPSTFT271MVWTIARIHF281EDYGCWDTIN291SSLWWIIKGP
301-350301ILTSILVNFI311LFICIIRILL321QKLRPPDIRK331SDSSPYSRLA341RSTLLLIPLF
351-400351GVHYIMFAFF361PDNFKPEVKM371VFELVVGSFQ381GFVVAILYCF391LNGEVQAELR
401-450401RKWRRWHLQG411VLGWNPKYRH421PSGGSNGATC431STQVSMLTRV441SPGARRSSSF
451-457451QAEVSLV
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
13 DBPTM SWISSPALM - - -
GPS-Palm: 0.79
Deep-Palm: 0.97
37 DBPTM SWISSPALM - - -
GPS-Palm: 0.76
Deep-Palm: 0.94
50 GPCR, family 2, extracellular hormone receptor domain GPCR, family 2, vasoactive intestinal peptide receptor 1 GPCR family 2, extracellular hormone receptor domain superfamily - -
Deep-Palm: 0.09
63 - - -
Deep-Palm: 0.31
72 - - -
Deep-Palm: 0.09
86 - - -
GPS-Palm: 0.84
Deep-Palm: 0.50
105 - - -
Deep-Palm: 0.39
122 - - -
Deep-Palm: 0.75
172 - - -
Deep-Palm: 0.17
208 - - -
Deep-Palm: 0.85
215 - - -
Deep-Palm: 0.10
225 - - -
Deep-Palm: 0.07
285 - - -
Deep-Palm: 0.03
314 - - -
GPS-Palm: 0.91
Deep-Palm: 0.87
389 - - -
Deep-Palm: 0.75
430 - - -
Deep-Palm: 0.71
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
50 C → Y 0.001887 SNP Missense Mutation UCEC
63 C → F 0.006944 SNP Missense Mutation TGCT
256 W → C 0.002033 SNP Missense Mutation LUSC
405 R → C 0.001887 SNP Missense Mutation UCEC
430 C → Y 0.002288 SNP Missense Mutation STAD