Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P35070 | BTC | Probetacellulin [Cleaved into: Betacellulin (BTC)] | Homo sapiens (Human) | 178 aa |
Protein Details: P35070 (BTC)
Protein Information
| Accession | P35070 |
|---|---|
| Protein Names | Probetacellulin [Cleaved into: Betacellulin (BTC)] |
| Gene Symbol | BTC |
| Organism | Homo sapiens (Human) |
| Length | 178 aa |
| Isoforms | No isoforms |
| Related PMIDs | No related PMIDs |
| Database Sources | dbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MDRAARCSGA11SSLPLLLALA21LGLVILHCVV31ADGNSTRSPE41TNGLLCGDPE
51-10051ENCAATTTQS61KRKGHFSRCP71KQYKHYCIKG81RCRFVVAEQT91PSCVCDEGYI
101-150101GARCERVDLF111YLRGDRGQIL121VICLIAVMVV131FIILVIGVCT141CCHPLRKRRK
151-178151RKKKEEEMET161LGKDITPINE171DIEETNIA
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 7 | - | - | - |
GPS-Palm: 0.85
Deep-Palm: 0.87
|
|
| 28 | - | - | - |
GPS-Palm: 0.71
Deep-Palm: 0.98
|
|
| 46 | - | - | - |
Deep-Palm: 0.72
|
|
| 53 | - | - | - |
GPS-Palm: 0.67
Deep-Palm: 0.69
|
|
| 69 | - | - | - |
Deep-Palm: 0.08
|
|
| 77 | - | - | - |
GPS-Palm: 0.71
Deep-Palm: 0.05
|
|
| 82 | - | - | - |
Deep-Palm: 0.02
|
|
| 93 | - | - | - |
Deep-Palm: 0.19
|
|
| 95 | - | - | - |
Deep-Palm: 0.26
|
|
| 104 | - | - | - |
GPS-Palm: 0.75
Deep-Palm: 0.28
|
|
| 123 | - | - | - |
GPS-Palm: 0.67
Deep-Palm: 0.71
|
|
| 139 | DBPTM SWISSPALM | - | - | - |
GPS-Palm: 0.96
Deep-Palm: 0.93
|
| 141 | DBPTM SWISSPALM | - | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.96
|
| 142 | DBPTM SWISSPALM | - | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.94
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 77 | C → C | 0.001887 | SNP | Silent | UCEC |
| 149 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 149 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |