Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P35363 Htr2a 5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) … Mus musculus (Mouse) 471 aa

Protein Details: P35363 (Htr2a)

Protein Information
AccessionP35363
Protein Names5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)
Gene SymbolHtr2a
OrganismMus musculus (Mouse)
Length471 aa
IsoformsNo isoforms
Related PMIDs 34200797
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MEILCEDNIS11LSSIPNSLMQ21LGDDSRLYPN31DFNSRDANTS41EASNWTIDAE
51-10051NRTNLSCEGY61LPPTCLSILH71LQEKNWSALL81TTVVIILTIA91GNILVIMAVS
101-150101LEKKLQNATN111YFLMSLAIAD121MLLGFLVMPV131SMLTILYGYR141WPLPSKLCAV
151-200151WIYLDVLFST161ASIMHLCAIS171LDRYVAIQNP181IHHSRFNSRT191KAFLKIIAVW
201-250201TISVGISMPI211PVFGLQDDSK221VFKEGSCLLA231DDNFVLIGSF241VAFFIPLTIM
251-300251VITYFLTIKS261LQKEATLCVS271DLSTRAKLSS281FSFLPQSSLS291SEKLFQRSIH
301-350301REPGSYAGRR311TMQSISNEQK321ACKVLGIVFF331LFVVMWCPFF341ITNIMAVICK
351-400351ESCNENVIGA361LLNVFVWIGY371LSSAVNPLVY381TLFNKTYRSA391FSRYIQCQYK
401-450401ENRKPLQLIL411VNTIPTLAYK421SSQLQVGQKK431NSQEDAEPTA441NDCSMVTLGN
451-471451QHSEEMCTDN461IETVNEKVSC471V
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
5 - - -
GPS-Palm: 0.81
Deep-Palm: 0.03
57 - - -
Deep-Palm: 0.74
65 - - -
Deep-Palm: 0.84
148 - - -
Deep-Palm: 0.36
167 - - -
Deep-Palm: 0.15
227 - - -
Deep-Palm: 0.93
268 - - -
GPS-Palm: 0.92
Deep-Palm: 0.96
322 - - -
GPS-Palm: 0.73
Deep-Palm: 0.32
337 - - -
Deep-Palm: 0.03
349 - - -
Deep-Palm: 0.05
353 - - -
Deep-Palm: 0.09
397 SWISSPALM DBPTM CYSMODDB -
Forebrain (28680068)
Brain (31311849)
GPS-Palm: 0.87
Deep-Palm: 0.78
443 - - -
Deep-Palm: 0.13
457 - - -
Deep-Palm: 0.02
470 - - -
GPS-Palm: 0.96
Deep-Palm: 0.01
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
Brain
Specificity: 1.000
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine