Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P35486 | Pdha1; Pdha-1 | Pyruvate dehydrogenase E1 component subunit … | Mus musculus (Mouse) | 390 aa |
Protein Details: P35486 (Pdha1)
Protein Information
| Accession | P35486 |
|---|---|
| Protein Names | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (EC 1.2.4.1) (PDHE1-A type I) |
| Gene Symbol | Pdha1; Pdha-1 |
| Organism | Mus musculus (Mouse) |
| Length | 390 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26165157 28526873 28680068 29733200 31311849 31772009 34200797 34884899 35358180 37925639 39008777 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.487
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
19
Liver tissue
Specificity: 0.487
19/19 (100.0%)
11
Brain tissue
Specificity: 0.282
11/12 (91.7%)
6
Liver membrane
Specificity: 0.154
6/6 (100.0%)
3
Neural Stem Cells
Specificity: 0.077
3/3 (100.0%)
0
Macrophage Raw 264.7
Specificity: 0.000
0/2 (0.0%)
0
Testis
Specificity: 0.000
0/2 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MRKMLAAVSR11VLAGSAQKPA21SRVLVASRNF31ANDATFEIKK41CDLHRLEEGP
51-10051PVTTVLTRED61GLKYYRMMQT71VRRMELKADQ81LYKQKIIRGF91CHLCDGQEAC
101-150101CVGLEAGINP111TDHLITAYRA121HGFTFTRGLP131VRAILAELTG141RRGGCAKGKG
151-200151GSMHMYAKNF161YGGNGIVGAQ171VPLGAGIALA181CKYNGKDEVC191LTLYGDGAAN
201-250201QGQIFEAYNM211AALWKLPCIF221ICENNRYGMG231TSVERAAAST241DYYKRGDFIP
251-300251GLRVDGMDIL261CVREATKFAA271AYCRSGKGPI281LMELQTYRYH291GHSMSDPGVS
301-350301YRTREEIQEV311RSKSDPIMLL321KDRMVNSNLA331SVEELKEIDV341EVRKEIEDAA
351-390351QFATADPEPP361LEELGYHIYS371SDPPFEVRGA381NQWIKFKSVS
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 41 | Experimental CYSMODDB DBPTM Prediction (Medium) | - | 26165157, 31311849, 39008777 |
| 91 | Experimental Prediction (Low) | Dehydrogenase E1 component | 34200797 |
| 94 | Experimental Prediction (Low) | Dehydrogenase E1 component | 34200797 |
| 100 | Experimental | Dehydrogenase E1 component | 34200797 |
| 101 | Experimental | Dehydrogenase E1 component | 34200797 |
| 145 | Prediction (High) | - | - |
| 181 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (High) | Dehydrogenase E1 component | 28680068 |
| 190 | Experimental | Dehydrogenase E1 component | 28680068 |
| 218 | Experimental Prediction (Medium) | Dehydrogenase E1 component | 35358180 |
| 222 | Experimental Prediction (Medium) | Dehydrogenase E1 component | 35358180 |
| 261 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (Medium) | Dehydrogenase E1 component | 28526873 |
| 273 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (High) | Dehydrogenase E1 component | 31311849, 28526873 |