Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P35486 | Pdha1 | Pyruvate dehydrogenase E1 component subunit … | Mus musculus (Mouse) | 390 aa |
Protein Details: P35486 (Pdha1)
Protein Information
| Accession | P35486 |
|---|---|
| Protein Names | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (EC 1.2.4.1) (PDHE1-A type I) |
| Gene Symbol | Pdha1 |
| Organism | Mus musculus (Mouse) |
| Length | 390 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 29733200 31311849 34200797 34884899 35358180 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MRKMLAAVSR11VLAGSAQKPA21SRVLVASRNF31ANDATFEIKK41CDLHRLEEGP
51-10051PVTTVLTRED61GLKYYRMMQT71VRRMELKADQ81LYKQKIIRGF91CHLCDGQEAC
101-150101CVGLEAGINP111TDHLITAYRA121HGFTFTRGLP131VRAILAELTG141RRGGCAKGKG
151-200151GSMHMYAKNF161YGGNGIVGAQ171VPLGAGIALA181CKYNGKDEVC191LTLYGDGAAN
201-250201QGQIFEAYNM211AALWKLPCIF221ICENNRYGMG231TSVERAAAST241DYYKRGDFIP
251-300251GLRVDGMDIL261CVREATKFAA271AYCRSGKGPI281LMELQTYRYH291GHSMSDPGVS
301-350301YRTREEIQEV311RSKSDPIMLL321KDRMVNSNLA331SVEELKEIDV341EVRKEIEDAA
351-390351QFATADPEPP361LEELGYHIYS371SDPPFEVRGA381NQWIKFKSVS
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 41 | SWISSPALM DBPTM CYSMODDB | - |
Brain
(31311849)
liver
(26165157)
brain
(39008777)
| - |
GPS-Palm: 0.80
Deep-Palm: 0.93
|
| 91 | Dehydrogenase E1 component |
Brain
(34200797)
|
Brain
(35358180)
|
GPS-Palm: 0.70
Deep-Palm: 0.77
|
|
| 94 | Dehydrogenase E1 component |
Brain
(34200797)
|
Brain
(35358180)
|
GPS-Palm: 0.71
Deep-Palm: 0.65
|
|
| 100 | Dehydrogenase E1 component |
Brain
(34200797)
|
Brain
(35358180)
|
Deep-Palm: 0.56
|
|
| 101 | Dehydrogenase E1 component |
Brain
(34200797)
|
Brain
(35358180)
|
Deep-Palm: 0.45
|
|
| 145 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.98
|
|
| 181 | SWISSPALM DBPTM CYSMODDB | Dehydrogenase E1 component |
Forebrain
(28680068)
|
Brain
(35358180)
|
GPS-Palm: 0.91
Deep-Palm: 0.97
|
| 190 | - | - | - |
Deep-Palm: 0.89
|
|
| 218 | - | - |
Brain
(35358180)
Brain
(31311849)
|
GPS-Palm: 0.84
Deep-Palm: 0.65
|
|
| 222 | - | - |
Brain
(35358180)
Brain
(31311849)
|
GPS-Palm: 0.82
Deep-Palm: 0.91
|
|
| 261 | SWISSPALM DBPTM CYSMODDB | Dehydrogenase E1 component |
Liver
(28526873)
|
Brain
(35358180)
|
GPS-Palm: 0.83
Deep-Palm: 0.94
|
| 273 | SWISSPALM DBPTM CYSMODDB | Dehydrogenase E1 component |
Brain
(31311849)
Liver
(28526873)
|
Brain
(35358180)
Brain
(31311849)
|
GPS-Palm: 0.90
Deep-Palm: 0.97
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.545
6
Liver
Specificity: 0.150
6/6 (100.0%)
5
Brain
Specificity: 0.125
5/5 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
29
Brain tissue (Mass)
Specificity: 0.725
29/56 (51.8%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.