Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P35527 | KRT9 | Keratin, type I cytoskeletal 9 … | Homo sapiens (Human) | 623 aa |
Protein Details: P35527 (KRT9)
Protein Information
| Accession | P35527 |
|---|---|
| Protein Names | Keratin, type I cytoskeletal 9 (Cytokeratin-9) (CK-9) (Keratin-9) (K9) |
| Gene Symbol | KRT9 |
| Organism | Homo sapiens (Human) |
| Length | 623 aa |
| Isoforms | No isoforms |
| Related PMIDs | 25914232 31382980 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSCRQFSSSY11LSRSGGGGGG21GLGSGGSIRS31SYSRFSSSGG41GGGGGRFSSS
51-10051SGYGGGSSRV61CGRGGGGSFG71YSYGGGSGGG81FSASSLGGGF91GGGSRGFGGA
101-150101SGGGYSSSGG111FGGGFGGGSG121GGFGGGYGSG131FGGFGGFGGG141AGGGDGGILT
151-200151ANEKSTMQEL161NSRLASYLDK171VQALEEANND181LENKIQDWYD191KKGPAAIQKN
201-250201YSPYYNTIDD211LKDQIVDLTV221GNNKTLLDID231NTRMTLDDFR241IKFEMEQNLR
251-300251QGVDADINGL261RQVLDNLTME271KSDLEMQYET281LQEELMALKK291NHKEEMSQLT
301-350301GQNSGDVNVE311INVAPGKDLT321KTLNDMRQEY331EQLIAKNRKD341IENQYETQIT
351-400351QIEHEVSSSG361QEVQSSAKEV371TQLRHGVQEL381EIELQSQLSK391KAALEKSLED
401-450401TKNRYCGQLQ411MIQEQISNLE421AQITDVRQEI431ECQNQEYSLL441LSIKMRLEKE
451-500451IETYHNLLEG461GQEDFESSGA471GKIGLGGRGG481SGGSYGRGSR491GGSGGSYGGG
501-550501GSGGGYGGGS511GSRGGSGGSY521GGGSGSGGGS531GGGYGGGSGG541GHSGGSGGGH
551-600551SGGSGGNYGG561GSGSGGGSGG571GYGGGSGSRG581GSGGSHGGGS591GFGGESGGSY
601-623601GGGEEASGSG611GGYGGGSGKS621SHS
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 3 | - | - | - |
GPS-Palm: 0.95
Deep-Palm: 0.03
|
|
| 61 | - | - |
Brain
(35358180)
|
GPS-Palm: 0.81
Deep-Palm: 0.87
|
|
| 406 | - | - |
Liver
(34884899)
Brain
(35358180)
Macrophage Raw 264.7
(29217618)
Unknown
(32651440)
|
GPS-Palm: 0.68
Deep-Palm: 0.96
|
|
| 432 | - | - |
Liver
(34884899)
Brain
(35358180)
Unknown
(32651440)
cerebral cortex
(36430497)
|
Deep-Palm: 0.85
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
3
CEM 174 cell
Specificity: 0.375
3/3 (100.0%)
1
U937 cell
Specificity: 0.125
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
Cerebral Cortex (Mass)
Specificity: 0.500
4/4 (100.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 51 | S → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 233 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 327 | R → C | 0.002033 | SNP | Missense Mutation | THCA |
| 404 | R → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 432 | C → Y | 0.002506 | SNP | Missense Mutation | COAD |