Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P35790 | CHKA | Choline kinase alpha (CK) (EC … | Homo sapiens (Human) | 457 aa |
Protein Details: P35790 (CHKA)
Protein Information
| Accession | P35790 |
|---|---|
| Protein Names | Choline kinase alpha (CK) (EC 2.7.1.32) (CHETK-alpha) (Ethanolamine kinase) (EK) (EC 2.7.1.82) |
| Gene Symbol | CHKA |
| Organism | Homo sapiens (Human) |
| Length | 457 aa |
| Isoforms | No isoforms |
| Related PMIDs | No related PMIDs |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MKTKFCTGGE11AEPSPLGLLL21SCGSGSAAPA31PGVGQQRDAA41SDLESKQLGG
51-10051QQPPLALPPP61PPLPLPLPLP71QPPPPQPPAD81EQPEPRTRRR91AYLWCKEFLP
101-150101GAWRGLREDE111FHISVIRGGL121SNMLFQCSLP131DTTATLGDEP141RKVLLRLYGA
151-200151ILQMRSCNKE161GSEQAQKENE171FQGAEAMVLE181SVMFAILAER191SLGPKLYGIF
201-250201PQGRLEQFIP211SRRLDTEELS221LPDISAEIAE231KMATFHGMKM241PFNKEPKWLF
251-300251GTMEKYLKEV261LRIKFTEESR271IKKLHKLLSY281NLPLELENLR291SLLESTPSPV
301-350301VFCHNDCQEG311NILLLEGREN321SEKQKLMLID331FEYSSYNYRG341FDIGNHFCEW
351-400351MYDYSYEKYP361FFRANIRKYP371TKKQQLHFIS381SYLPAFQNDF391ENLSTEEKSI
401-450401IKEEMLLEVN411RFALASHFLW421GLWSIVQAKI431SSIEFGYMDY441AQARFDAYFH
451-457451QKRKLGV
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 6 | - |
HeLa
(37611173)
| - |
GPS-Palm: 0.90
Deep-Palm: 0.15
|
|
| 22 | - | - | - |
Deep-Palm: 0.98
|
|
| 95 | - | - | - |
GPS-Palm: 0.88
Deep-Palm: 0.94
|
|
| 127 | - | - | - |
GPS-Palm: 0.71
Deep-Palm: 0.90
|
|
| 157 | - | - | - |
GPS-Palm: 0.83
Deep-Palm: 0.95
|
|
| 303 | - | - | - |
Deep-Palm: 0.59
|
|
| 307 | - | - | - |
Deep-Palm: 0.26
|
|
| 348 | - | - | - |
Deep-Palm: 0.02
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 98 | F → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 445 | F → C | 0.001887 | SNP | Missense Mutation | UCEC |