Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P35998-2 | PSMC2 | 26S proteasome regulatory subunit 7 … | Homo sapiens (Human) | 296 aa |
Protein Details: P35998-2 (PSMC2)
Protein Information
| Accession | P35998-2 |
|---|---|
| Protein Names | 26S proteasome regulatory subunit 7 (26S proteasome AAA-ATPase subunit RPT1) (Proteasome 26S subunit ATPase 2) |
| Gene Symbol | PSMC2 |
| Organism | Homo sapiens (Human) |
| Length | 296 aa |
| Isoforms | |
| Related PMIDs | 31251020 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MRVGVDRNKY11QIHIPLPPKI21DPTVTMMQVE31EKPDVTYSDV41GGCKEQIEKL
51-10051REVVETPLLH61PERFVNLGIE71PPKGVLLFGP81PGTGKTLCAR91AVANRTDACF
101-150101IRVIGSELVQ111KYVGEGARMV121RELFEMARTK131KACLIFFDEI141DAIGGARFDD
151-200151GAGGDNEVQR161TMLELINQLD171GFDPRGNIKV181LMATNRPDTL191DPALMRPGRL
201-250201DRKIEFSLPD211LEGRTHIFKI221HARSMSVERD231IRFELLARLC241PNSTGAEIRS
251-296251VCTEAGMFAI261RARRKIATEK271DFLEAVNKVI281KSYAKFSATP291RYMTYN
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 98 | - | - | - |
Deep-Palm: 0.83
|
|
| 180 | - | - | - |
Deep-Palm: 0.91
|
|
| 225 | - | - | - |
Deep-Palm: 0.97
|
|
| 236 | - | - | - |
Deep-Palm: 0.98
|
|
| 240 | - | - | - |
GPS-Palm: 0.90
|
|
| 270 | - | - | - |
Deep-Palm: 0.94
|
|
| 377 | - | - | - |
Deep-Palm: 0.97
|
|
| 389 | - | - | - |
Deep-Palm: 0.96
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
LNCaP
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 258 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 258 | R → C | 0.007299 | SNP | Missense Mutation | READ |
| 360 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 428 | R → C | 0.008130 | SNP | Missense Mutation | THYM |