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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P36894 BMPR1A; ACVRLK3; ALK3 Bone morphogenetic protein receptor type-1A … Homo sapiens (Human) 532 aa

Protein Details: P36894 (BMPR1A)

Protein Information
Accession P36894
Protein Names Bone morphogenetic protein receptor type-1A (BMP type-1A receptor) (BMPR-1A) (EC 2.7.11.30) (Activin receptor-like kinase 3) (ALK-3) (Serine/threonine-protein kinase receptor R5) (SKR5) (CD antigen CD292)
Gene Symbol BMPR1A; ACVRLK3; ALK3
Organism Homo sapiens (Human)
Length 532 aa
Isoforms No isoforms
Related PMIDs 31251020 32944167
Database Sources SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.812
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
13
LNCaP cells
Specificity: 0.812
13/46 (28.3%)
3
PC3 cells
Specificity: 0.188
3/4 (75.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MPQLYIYIRL11LGAYLFIISR21VQGQNLDSML31HGTGMKSDSD41QKKSENGVTL
51-10051APEDTLPFLK61CYCSGHCPDD71AINNTCITNG81HCFAIIEEDD91QGETTLASGC
101-150101MKYEGSDFQC111KDSPKAQLRR121TIECCRTNLC131NQYLQPTLPP141VVIGPFFDGS
151-200151IRWLVLLISM161AVCIIAMIIF171SSCFCYKHYC181KSISSRRRYN191RDLEQDEAFI
201-250201PVGESLKDLI211DQSQSSGSGS221GLPLLVQRTI231AKQIQMVRQV241GKGRYGEVWM
251-300251GKWRGEKVAV261KVFFTTEEAS271WFRETEIYQT281VLMRHENILG291FIAADIKGTG
301-350301SWTQLYLITD311YHENGSLYDF321LKCATLDTRA331LLKLAYSAAC341GLCHLHTEIY
351-400351GTQGKPAIAH361RDLKSKNILI371KKNGSCCIAD381LGLAVKFNSD391TNEVDVPLNT
401-450401RVGTKRYMAP411EVLDESLNKN421HFQPYIMADI431YSFGLIIWEM441ARRCITGGIV
451-500451EEYQLPYYNM461VPSDPSYEDM471REVVCVKRLR481PIVSNRWNSD491ECLRAVLKLM
501-532501SECWAHNPAS511RLTALRIKKT521LAKMVESQDV531KI
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
124 Prediction (Low) - -
125 Prediction (Medium) - -
173 SWISSPALM Prediction (Medium) - -
175 SWISSPALM Prediction (Medium) - -
180 SWISSPALM Prediction (Low) - -
376 Prediction (Medium) - -
377 Prediction (High) - -
444 Prediction (Medium) - -
475 Prediction (Low) - -
492 Prediction (Low) - -
503 Prediction (Medium) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
61 C → Y 0.002747 SNP Missense Mutation LIHC
76 C → Y 0.001887 SNP Missense Mutation UCEC
173 C → C 0.002506 SNP Silent COAD
179 Y → C 0.001887 SNP Missense Mutation UCEC
191 R → C 0.002141 SNP Missense Mutation SKCM
245 Y → C 0.002506 SNP Missense Mutation COAD
278 Y → C 0.002020 SNP Missense Mutation PRAD
376 C → R 0.002288 SNP Missense Mutation STAD
471 R → C 0.001887 SNP Missense Mutation UCEC
82* C → ? 0.002545 SNP Nonsense Mutation GBM