Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P38060 | Hmgcl | Hydroxymethylglutaryl-CoA lyase, mitochondrial (HL) (HMG-CoA … | Mus musculus (Mouse) | 325 aa |
Protein Details: P38060 (Hmgcl)
Protein Information
| Accession | P38060 |
|---|---|
| Protein Names | Hydroxymethylglutaryl-CoA lyase, mitochondrial (HL) (HMG-CoA lyase) (EC 4.1.3.4) (3-hydroxy-3-methylglutarate-CoA lyase) |
| Gene Symbol | Hmgcl |
| Organism | Mus musculus (Mouse) |
| Length | 325 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26165157 28526873 31772009 34884899 35358180 35477839 37925639 39008777 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.576
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
19
Liver tissue
Specificity: 0.576
19/19 (100.0%)
6
Liver membrane
Specificity: 0.182
6/6 (100.0%)
3
Brain tissue
Specificity: 0.091
3/12 (25.0%)
3
Neural Stem Cells
Specificity: 0.091
3/3 (100.0%)
2
Testis
Specificity: 0.061
2/2 (100.0%)
0
Macrophage Raw 264.7
Specificity: 0.000
0/2 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MASVRKAFPR11RLVGLTSLRA21VSTSSMGTLP31KQVKIVEVGP41RDGLQNEKSI
51-10051VPTPVKIRLI61DMLSEAGLPV71IEATSFVSPK81WVPQMADHSD91VLKGIQKFPG
101-150101INYPVLTPNM111KGFEEAVAAG121AKEVSVFGAV131SELFTRKNAN141CSIEESFQRF
151-200151AGVMQAAQAA161SISVRGYVSC171ALGCPYEGKV181SPAKVAEVAK191KLYSMGCYEI
201-250201SLGDTIGVGT211PGLMKDMLTA221VMHEVPVTAL231AVHCHDTYGQ241ALANTLVALQ
251-300251MGVSVVDSSV261AGLGGCPYAK271GASGNLATED281LVYMLNGLGI291HTGVNLQKLL
301-325301EAGDFICQAL311NRKTSSKVAQ321ATCKL
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 141 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (Medium) | HMGL-like | 26165157, 28526873 |
| 170 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (High) | - | 28526873 |
| 174 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (Medium) | - | 28526873 |
| 307 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (High) | - | 26165157, 28526873 |
| 323 | Experimental Prediction (High) | - | 39008777 |