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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P38646 HSPA9; GRP75; HSPA9B; mt-HSP70 Stress-70 protein, mitochondrial (EC 3.6.4.10) … Homo sapiens (Human) 679 aa

Protein Details: P38646 (HSPA9)

Protein Information
Accession P38646
Protein Names Stress-70 protein, mitochondrial (EC 3.6.4.10) (75 kDa glucose-regulated protein) (GRP-75) (Heat shock 70 kDa protein 9) (Heat shock protein family A member 9) (Mortalin) (MOT) (Peptide-binding protein 74) (PBP74)
Gene Symbol HSPA9; GRP75; HSPA9B; mt-HSP70
Organism Homo sapiens (Human)
Length 679 aa
Isoforms No isoforms
Related PMIDs 21076176 29733200 31251020 31382980 32944167 36430497
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.562
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
36
LNCaP cells
Specificity: 0.562
36/46 (78.3%)
10
HAP1 cells
Specificity: 0.156
10/10 (100.0%)
6
Jurkat T cells
Specificity: 0.094
6/25 (24.0%)
4
293T cells
Specificity: 0.062
4/10 (40.0%)
4
Cerebral cortex
Specificity: 0.062
4/4 (100.0%)
3
PC3 cells
Specificity: 0.047
3/4 (75.0%)
1
U937 cells
Specificity: 0.016
1/1 (100.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MISASRAAAA11RLVGAAASRG21PTAARHQDSW31NGLSHEAFRL41VSRRDYASEA
51-10051IKGAVVGIDL61GTTNSCVAVM71EGKQAKVLEN81AEGARTTPSV91VAFTADGERL
101-150101VGMPAKRQAV111TNPNNTFYAT121KRLIGRRYDD131PEVQKDIKNV141PFKIVRASNG
151-200151DAWVEAHGKL161YSPSQIGAFV171LMKMKETAEN181YLGHTAKNAV191ITVPAYFNDS
201-250201QRQATKDAGQ211ISGLNVLRVI221NEPTAAALAY231GLDKSEDKVI241AVYDLGGGTF
251-300251DISILEIQKG261VFEVKSTNGD271TFLGGEDFDQ281ALLRHIVKEF291KRETGVDLTK
301-350301DNMALQRVRE311AAEKAKCELS321SSVQTDINLP331YLTMDSSGPK341HLNMKLTRAQ
351-400351FEGIVTDLIR361RTIAPCQKAM371QDAEVSKSDI381GEVILVGGMT391RMPKVQQTVQ
401-450401DLFGRAPSKA411VNPDEAVAIG421AAIQGGVLAG431DVTDVLLLDV441TPLSLGIETL
451-500451GGVFTKLINR461NTTIPTKKSQ471VFSTAADGQT481QVEIKVCQGE491REMAGDNKLL
501-550501GQFTLIGIPP511APRGVPQIEV521TFDIDANGIV531HVSAKDKGTG541REQQIVIQSS
551-600551GGLSKDDIEN561MVKNAEKYAE571EDRRKKERVE581AVNMAEGIIH591DTETKMEEFK
601-650601DQLPADECNK611LKEEISKMRE621LLARKDSETG631ENIRQAASSL641QQASLKLFEM
651-679651AYKKMASERE661GSGSSGTGEQ671KEDQKEEKQ
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
66 Prediction (Medium) - -
317 Prediction (Medium) - -
366 CYSMODDB SWISSPALM DBPTM Prediction (High) Hsp70 protein -
608 Prediction (Medium) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
148 S → C 0.002033 SNP Missense Mutation LUSC
599 F → C 0.001887 SNP Missense Mutation UCEC