Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P39023 | RPL3; OK/SW-cl.32 | Large ribosomal subunit protein uL3 … | Homo sapiens (Human) | 403 aa |
Protein Details: P39023 (RPL3)
Protein Information
| Accession | P39023 |
|---|---|
| Protein Names | Large ribosomal subunit protein uL3 (60S ribosomal protein L3) (HIV-1 TAR RNA-binding protein B) (TARBP-B) |
| Gene Symbol | RPL3; OK/SW-cl.32 |
| Organism | Homo sapiens (Human) |
| Length | 403 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19137006 26865113 29575903 29733200 31251020 31382980 32944167 36430497 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.571
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
36
LNCaP cells
Specificity: 0.571
36/46 (78.3%)
10
HAP1 cells
Specificity: 0.159
10/10 (100.0%)
5
Jurkat T cells
Specificity: 0.079
5/25 (20.0%)
4
293T cells
Specificity: 0.063
4/10 (40.0%)
3
PC3 cells
Specificity: 0.048
3/4 (75.0%)
3
Cerebral cortex
Specificity: 0.048
3/4 (75.0%)
1
U937 cells
Specificity: 0.016
1/1 (100.0%)
1
HeLa cells
Specificity: 0.016
1/1 (100.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MSHRKFSAPR11HGSLGFLPRK21RSSRHRGKVK31SFPKDDPSKP41VHLTAFLGYK
51-10051AGMTHIVREV61DRPGSKVNKK71EVVEAVTIVE81TPPMVVVGIV91GYVETPRGLR
101-150101TFKTVFAEHI111SDECKRRFYK121NWHKSKKKAF131TKYCKKWQDE141DGKKQLEKDF
151-200151SSMKKYCQVI161RVIAHTQMRL171LPLRQKKAHL181MEIQVNGGTV191AEKLDWARER
201-250201LEQQVPVNQV211FGQDEMIDVI221GVTKGKGYKG231VTSRWHTKKL241PRKTHRGLRK
251-300251VACIGAWHPA261RVAFSVARAG271QKGYHHRTEI281NKKIYKIGQG291YLIKDGKLIK
301-350301NNASTDYDLS311DKSINPLGGF321VHYGEVTNDF331VMLKGCVVGT341KKRVLTLRKS
351-400351LLVQTKRRAL361EKIDLKFIDT371TSKFGHGRFQ381TMEEKKAFMG391PLKKDRIAKE
401-403401EGA
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 134 | Prediction (Medium) | - | - |
| 157 | Experimental Prediction (Medium) | Ribosomal protein L3 | 26865113 |
| 253 | CYSMODDB SWISSPALM DBPTM Prediction (High) | Ribosomal protein L3 | - |
| 336 | Prediction (High) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 249 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 291 | Y → C | 0.002506 | SNP | Missense Mutation | COAD |