Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P40142 | Tkt | Transketolase (TK) (EC 2.2.1.1) (P68) | Mus musculus (Mouse) | 623 aa |
Protein Details: P40142 (Tkt)
Protein Information
| Accession | P40142 |
|---|---|
| Protein Names | Transketolase (TK) (EC 2.2.1.1) (P68) |
| Gene Symbol | Tkt |
| Organism | Mus musculus (Mouse) |
| Length | 623 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29217618 29733200 31311849 34200797 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MEGYHKPDQQ11KLQALKDTAN21RLRISSIQAT31TAAGSGHPTS41CCSAAEIMAV
51-10051LFFHTMRYKA61LDPRNPHNDR71FVLSKGHAAP81ILYAVWAEAG91FLPEAELLNL
101-150101RKISSDLDGH111PVPKQAFTDV121ATGSLGQGLG131AACGMAYTGK141YFDKASYRVY
151-200151CMLGDGEVSE161GSVWEAMAFA171GIYKLDNLVA181IFDINRLGQS191DPAPLQHQVD
201-250201IYQKRCEAFG211WHTIIVDGHS221VEELCKAFGQ231AKHQPTAIIA241KTFKGRGITG
251-300251IEDKEAWHGK261PLPKNMAEQI271IQEIYSQVQS281KKKILATPPQ291EDAPSVDIAN
301-350301IRMPTPPSYK311VGDKIATRKA321YGLALAKLGH331ASDRIIALDG341DTKNSTFSEL
351-400351FKKEHPDRFI361ECYIAEQNMV371SIAVGCATRD381RTVPFCSTFA391AFFTRAFDQI
401-450401RMAAISESNI411NLCGSHCGVS421IGEDGPSQMA431LEDLAMFRSV441PMSTVFYPSD
451-500451GVATEKAVEL461AANTKGICFI471RTSRPENAII481YSNNEDFQVG491QAKVVLKSKD
501-550501DQVTVIGAGV511TLHEALAAAE521SLKKDKISIR531VLDPFTIKPL541DRKLILDSAR
551-600551ATKGRILTVE561DHYYEGGIGE571AVSAAVVGEP581GVTVTRLAVS591QVPRSGKPAE
601-623601LLKMFGIDKD611AIVQAVKGLV621TKG
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 41 | Thiamin diphosphate-binding fold Transketolase-like | - | - |
Deep-Palm: 0.43
|
|
| 42 | Thiamin diphosphate-binding fold Transketolase-like | - | - |
Deep-Palm: 0.52
|
|
| 133 | - | - |
Brain
(35358180)
|
GPS-Palm: 0.72
Deep-Palm: 0.89
|
|
| 151 | - | - | - |
Deep-Palm: 0.70
|
|
| 206 | - | - | - |
Deep-Palm: 0.08
|
|
| 225 | - | - | - |
Deep-Palm: 0.81
|
|
| 362 | - | - | - |
Deep-Palm: 0.70
|
|
| 376 | Transketolase pyrimidine binding domain |
Brain
(34200797)
| - |
GPS-Palm: 0.87
Deep-Palm: 0.44
|
|
| 386 | SWISSPALM DBPTM CYSMODDB | Transketolase, pyrimidine binding domain |
Brain
(31311849)
liver
(26165157)
|
Brain
(35358180)
Brain
(31311849)
|
GPS-Palm: 0.88
Deep-Palm: 0.81
|
| 413 | - | - | - |
Deep-Palm: 0.55
|
|
| 417 | - | - | - |
Deep-Palm: 0.59
|
|
| 468 | - |
Brain
(31311849)
| - |
GPS-Palm: 0.93
Deep-Palm: 0.96
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.385
5
Brain
Specificity: 0.143
5/5 (100.0%)
5
Liver
Specificity: 0.143
5/5 (100.0%)
2
Testis
Specificity: 0.057
2/2 (100.0%)
1
Raw 264.7
Specificity: 0.029
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
22
Brain tissue (Mass)
Specificity: 0.629
22/56 (39.3%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.