Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P40222 | TXLNA | Alpha-taxilin | Homo sapiens (Human) | 546 aa |
Protein Details: P40222 (TXLNA)
Protein Information
| Accession | P40222 |
|---|---|
| Protein Names | Alpha-taxilin |
| Gene Symbol | TXLNA |
| Organism | Homo sapiens (Human) |
| Length | 546 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 31382980 |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MKNQDKKNGA11AKQSNPKSSP21GQPEAGPEGA31QERPSQAAPA41VEAEGPGSSQ
51-10051APRKPEGAQA61RTAQSGALRD71VSEELSRQLE81DILSTYCVDN91NQGGPGEDGA
101-150101QGEPAEPEDA111EKSRTYVARN121GEPEPTPVVN131GEKEPSKGDP141NTEEIRQSDE
151-200151VGDRDHRRPQ161EKKKAKGLGK171EITLLMQTLN181TLSTPEEKLA191ALCKKYAELL
201-250201EEHRNSQKQM211KLLQKKQSQL221VQEKDHLRGE231HSKAVLARSK241LESLCRELQR
251-300251HNRSLKEEGV261QRAREEEEKR271KEVTSHFQVT281LNDIQLQMEQ291HNERNSKLRQ
301-350301ENMELAERLK311KLIEQYELRE321EHIDKVFKHK331DLQQQLVDAK341LQQAQEMLKE
351-400351AEERHQREKD361FLLKEAVESQ371RMCELMKQQE381THLKQQLALY391TEKFEEFQNT
401-450401LSKSSEVFTT411FKQEMEKMTK421KIKKLEKETT431MYRSRWESSN441KALLEMAEEK
451-500451TVRDKELEGL461QVKIQRLEKL471CRALQTERND481LNKRVQDLSA491GGQGSLTDSG
501-546501PERRPEGPGA511QAPSSPRVTE521APCYPGAPST531EASGQTGPQE541PTSARA
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 87 | - | - | - |
Deep-Palm: 0.88
|
|
| 193 | - | - | - |
Deep-Palm: 0.98
|
|
| 245 | - | - | - |
GPS-Palm: 0.88
Deep-Palm: 0.96
|
|
| 373 | - | - | - |
Deep-Palm: 0.88
|
|
| 471 | - | - | - |
GPS-Palm: 0.87
Deep-Palm: 0.94
|
|
| 523 | - | - | - |
Deep-Palm: 0.90
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
1
HAP1 cell
Specificity: 0.500
1/1 (100.0%)
1
U937 cell
Specificity: 0.500
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 69 | R → C | 0.007299 | SNP | Missense Mutation | READ |
| 69 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 69 | R → C | 0.003460 | SNP | Missense Mutation | CESC |
| 245 | C → Y | 0.001887 | SNP | Missense Mutation | UCEC |
| 259 | G → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 319 | R → C | 0.002294 | SNP | Missense Mutation | OV |