Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P41091 EIF2S3; EIF2G Eukaryotic translation initiation factor 2 … Homo sapiens (Human) 472 aa

Protein Details: P41091 (EIF2S3)

Protein Information
Accession P41091
Protein Names Eukaryotic translation initiation factor 2 subunit 3 (EC 3.6.5.3) (Eukaryotic translation initiation factor 2 subunit gamma X) (eIF2-gamma X) (eIF2gX)
Gene Symbol EIF2S3; EIF2G
Organism Homo sapiens (Human)
Length 472 aa
Isoforms No isoforms
Related PMIDs 19801377 24357059 29733200 31251020 31382980 32944167 36430497
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.596
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
34
LNCaP cells
Specificity: 0.596
34/46 (73.9%)
10
HAP1 cells
Specificity: 0.175
10/10 (100.0%)
4
293T cells
Specificity: 0.070
4/10 (40.0%)
4
Cerebral cortex
Specificity: 0.070
4/4 (100.0%)
3
PC3 cells
Specificity: 0.053
3/4 (75.0%)
1
U937 cells
Specificity: 0.018
1/1 (100.0%)
1
Endothelial cells
Specificity: 0.018
1/2 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAGGEAGVTL11GQPHLSRQDL21TTLDVTKLTP31LSHEVISRQA41TINIGTIGHV
51-10051AHGKSTVVKA61ISGVHTVRFK71NELERNITIK81LGYANAKIYK91LDDPSCPRPE
101-150101CYRSCGSSTP111DEFPTDIPGT121KGNFKLVRHV131SFVDCPGHDI141LMATMLNGAA
151-200151VMDAALLLIA161GNESCPQPQT171SEHLAAIEIM181KLKHILILQN191KIDLVKESQA
201-250201KEQYEQILAF211VQGTVAEGAP221IIPISAQLKY231NIEVVCEYIV241KKIPVPPRDF
251-300251TSEPRLIVIR261SFDVNKPGCE271VDDLKGGVAG281GSILKGVLKV291GQEIEVRPGI
301-350301VSKDSEGKLM311CKPIFSKIVS321LFAEHNDLQY331AAPGGLIGVG341TKIDPTLCRA
351-400351DRMVGQVLGA361VGALPEIFTE371LEISYFLLRR381LLGVRTEGDK391KAAKVQKLSK
401-450401NEVLMVNIGS411LSTGGRVSAV421KADLGKIVLT431NPVCTEVGEK441IALSRRVEKH
451-472451WRLIGWGQIR461RGVTIKPTVD471DD
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
105 Experimental CYSMODDB SWISSPALM DBPTM - 19801377
236 Prediction (Low) - -
269 Prediction (Medium) - -
311 Prediction (Low) - -
348 Prediction (Medium) - -
434 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons