Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P41091 | EIF2S3 | Eukaryotic translation initiation factor 2 … | Homo sapiens (Human) | 472 aa |
Protein Details: P41091 (EIF2S3)
Protein Information
| Accession | P41091 |
|---|---|
| Protein Names | Eukaryotic translation initiation factor 2 subunit 3 (EC 3.6.5.3) (Eukaryotic translation initiation factor 2 subunit gamma X) (eIF2-gamma X) (eIF2gX) |
| Gene Symbol | EIF2S3 |
| Organism | Homo sapiens (Human) |
| Length | 472 aa |
| Isoforms | No isoforms |
| Related PMIDs | 24357059 29733200 31251020 31382980 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAGGEAGVTL11GQPHLSRQDL21TTLDVTKLTP31LSHEVISRQA41TINIGTIGHV
51-10051AHGKSTVVKA61ISGVHTVRFK71NELERNITIK81LGYANAKIYK91LDDPSCPRPE
101-150101CYRSCGSSTP111DEFPTDIPGT121KGNFKLVRHV131SFVDCPGHDI141LMATMLNGAA
151-200151VMDAALLLIA161GNESCPQPQT171SEHLAAIEIM181KLKHILILQN191KIDLVKESQA
201-250201KEQYEQILAF211VQGTVAEGAP221IIPISAQLKY231NIEVVCEYIV241KKIPVPPRDF
251-300251TSEPRLIVIR261SFDVNKPGCE271VDDLKGGVAG281GSILKGVLKV291GQEIEVRPGI
301-350301VSKDSEGKLM311CKPIFSKIVS321LFAEHNDLQY331AAPGGLIGVG341TKIDPTLCRA
351-400351DRMVGQVLGA361VGALPEIFTE371LEISYFLLRR381LLGVRTEGDK391KAAKVQKLSK
401-450401NEVLMVNIGS411LSTGGRVSAV421KADLGKIVLT431NPVCTEVGEK441IALSRRVEKH
451-472451WRLIGWGQIR461RGVTIKPTVD471DD
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 96 | - | - | - |
Deep-Palm: 0.63
|
|
| 101 | - | - | - |
Deep-Palm: 0.35
|
|
| 105 | SWISSPALM DBPTM CYSMODDB | - |
SW480 cell line
(26865113)
|
Unknown
(32651440)
cerebral cortex
(36430497)
|
Deep-Palm: 0.34
|
| 135 | - | - | - |
Deep-Palm: 0.89
|
|
| 165 | - | - | - |
Deep-Palm: 0.96
|
|
| 236 | - | - |
Unknown
(32651440)
|
GPS-Palm: 0.70
Deep-Palm: 0.92
|
|
| 269 | - | - | - |
GPS-Palm: 0.79
Deep-Palm: 0.96
|
|
| 311 | - | - | - |
GPS-Palm: 0.72
Deep-Palm: 0.93
|
|
| 348 | - | - | - |
GPS-Palm: 0.87
Deep-Palm: 0.98
|
|
| 434 | - | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.93
Deep-Palm: 0.98
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.333
4
cerebral cortex
Specificity: 0.286
4/4 (100.0%)
3
LNCaP
Specificity: 0.214
3/3 (100.0%)
2
HAP1 cell
Specificity: 0.143
2/2 (100.0%)
1
U937 cell
Specificity: 0.071
1/1 (100.0%)
1
293T cell
Specificity: 0.071
1/1 (100.0%)
1
HUVECs
Specificity: 0.071
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
Cerebral Cortex (Mass)
Specificity: 0.143
2/4 (50.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.