Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P41216 | Acsl1 | Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3) … | Mus musculus (Mouse) | 699 aa |
Protein Details: P41216 (Acsl1)
Protein Information
| Accession | P41216 |
|---|---|
| Protein Names | Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain acyl-CoA synthetase 1) (LACS 1) (Phytanate--CoA ligase) (EC 6.2.1.24) |
| Gene Symbol | Acsl1 |
| Organism | Mus musculus (Mouse) |
| Length | 699 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 29733200 34884899 35358180 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MEVHELFRYF11RMPELIDIRQ21YVRTLPTNTL31MGFGAFAALT41TFWYATRPKA
51-10051LKPPCDLSMQ61SVEIAGTTDG71IRRSAVLEDD81KLLVYYYDDV91RTMYDGFQRG
101-150101IQVSNNGPCL111GSRKPNQPYE121WISYKEVAEL131AECIGSGLIQ141KGFKPCSEQF
151-200151IGLFSQNRPE161WVIVEQGCFS171YSMVVVPLYD181TLGADAITYI191VNKAELSVIF
201-250201ADKPEKAKLL211LEGVENKLTP221CLKIIVIMDS231YGSDLVERGK241KCGVEIISLK
251-300251ALEDLGRVNR261VKPKPPEPED271LAIICFTSGT281TGNPKGAMIT291HQNIINDCSG
301-350301FIKATESAFI311ASTDDVLISF321LPLAHMFETV331VECVMLCHGA341KIGFFQGDIR
351-400351LLMDDLKVLQ361PTIFPVVPRL371LNRMFDRIFG381QANTSLKRWL391LDFASKRKEA
401-450401ELRSGIVRNN411SLWDKLIFHK421IQSSLGGKVR431LMITGAAPVS441ATVLTFLRTA
451-500451LGCQFYEGYG461QTECTAGCCL471SLPGDWTAGH481VGAPMPCNYV491KLVDVEEMNY
501-550501LASKGEGEVC511VKGANVFKGY521LKDPARTAEA531LDKDGWLHTG541DIGKWLPNGT
551-600551LKIIDRKKHI561FKLAQGEYIA571PEKIENIYLR581SEAVAQVFVH591GESLQAFLIA
601-650601VVVPDVESLP611SWAQKRGLQG621SFEELCRNKD631INKAILDDLL641KLGKEAGLKP
651-699651FEQVKGIAVH661PELFSIDNGL671LTPTLKAKRP681ELRNYFRSQI691DELYATIKI
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 55 | SWISSPALM DBPTM CYSMODDB | - |
Liver
(28526873)
|
Liver
(34884899)
|
GPS-Palm: 0.84
Deep-Palm: 0.80
|
| 109 | SWISSPALM DBPTM CYSMODDB | - |
Liver
(28526873)
liver
(26165157)
|
Brain
(35358180)
|
GPS-Palm: 0.77
Deep-Palm: 0.40
|
| 133 | SWISSPALM DBPTM CYSMODDB | - |
Liver
(28526873)
|
Liver
(34884899)
Brain
(35358180)
|
GPS-Palm: 0.90
Deep-Palm: 0.80
|
| 146 | - | - | - |
GPS-Palm: 0.74
Deep-Palm: 0.70
|
|
| 168 | - | - | - |
Deep-Palm: 0.19
|
|
| 221 | SWISSPALM DBPTM CYSMODDB | - | - | - |
GPS-Palm: 0.78
Deep-Palm: 0.97
|
| 242 | SWISSPALM DBPTM CYSMODDB | - |
Liver
(28526873)
| - |
GPS-Palm: 0.77
Deep-Palm: 0.97
|
| 275 | SWISSPALM DBPTM CYSMODDB | AMP-binding enzyme |
Liver
(28526873)
|
Liver
(34884899)
|
Deep-Palm: 0.89
|
| 298 | SWISSPALM DBPTM CYSMODDB | AMP-binding enzyme |
Liver
(28526873)
| - |
GPS-Palm: 0.73
Deep-Palm: 0.22
|
| 333 | - | - | - |
Deep-Palm: 0.22
|
|
| 337 | - | - | - |
GPS-Palm: 0.80
Deep-Palm: 0.61
|
|
| 453 | - | - | - |
GPS-Palm: 0.75
Deep-Palm: 0.95
|
|
| 464 | - | - | - |
Deep-Palm: 0.84
|
|
| 468 | - | - | - |
Deep-Palm: 0.16
|
|
| 469 | - | - | - |
Deep-Palm: 0.60
|
|
| 487 | - | - | - |
Deep-Palm: 0.41
|
|
| 510 | - | - | - |
GPS-Palm: 0.67
Deep-Palm: 0.94
|
|
| 626 | SWISSPALM DBPTM CYSMODDB | - |
Liver
(28526873)
liver
(26165157)
| - |
GPS-Palm: 0.84
Deep-Palm: 0.98
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
6
Liver
Specificity: 0.429
6/6 (100.0%)
2
Brain
Specificity: 0.143
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
6
Brain tissue (Mass)
Specificity: 0.429
6/56 (10.7%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.