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UniProt ID Gene Symbol Protein Name Organism Length Action
P41220 RGS2 Regulator of G-protein signaling 2 … Homo sapiens (Human) 211 aa

Protein Details: P41220 (RGS2)

Protein Information
AccessionP41220
Protein NamesRegulator of G-protein signaling 2 (RGS2) (Cell growth-inhibiting gene 31 protein) (G0/G1 switch regulatory protein 8)
Gene SymbolRGS2
OrganismHomo sapiens (Human)
Length211 aa
IsoformsNo isoforms
Related PMIDs No related PMIDs
Database SourcesdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MQSAMFLAVQ11HDCRPMDKSA21GSGHKSEEKR31EKMKRTLLKD41WKTRLSYFLQ
51-10051NSSTPGKPKT61GKKSKQQAFI71KPSPEEAQLW81SEAFDELLAS91KYGLAAFRAF
101-150101LKSEFCEENI111EFWLACEDFK121KTKSPQKLSS131KARKIYTDFI141EKEAPKEINI
151-200151DFQTKTLIAQ161NIQEATSGCF171TTAQKRVYSL181MENNSYPRFL191ESEFYQDLCK
201-211201KPQITTEPHA211T
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
13 - - -
Deep-Palm: 0.05
106 DBPTM SWISSPALM Regulator of G protein signaling domain - -
Deep-Palm: 0.88
116 DBPTM SWISSPALM Regulator of G protein signaling domain - -
GPS-Palm: 0.91
Deep-Palm: 0.92
169 - - -
GPS-Palm: 0.76
Deep-Palm: 0.64
199 DBPTM SWISSPALM Regulator of G protein signaling domain - -
Deep-Palm: 0.11
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
13 C → R 0.001887 SNP Missense Mutation UCEC
199 C → S 0.002506 SNP Missense Mutation COAD