Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P42932 Cct8 T-complex protein 1 subunit theta … Mus musculus (Mouse) 548 aa

Protein Details: P42932 (Cct8)

Protein Information
AccessionP42932
Protein NamesT-complex protein 1 subunit theta (TCP-1-theta) (EC 3.6.1.-) (CCT-theta)
Gene SymbolCct8
OrganismMus musculus (Mouse)
Length548 aa
IsoformsNo isoforms
Related PMIDs 28526873 29217618 29660268 29733200 34200797 34884899 35358180 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MALHVPKAPG11FAQMLKDGAK21HFSGLEEAVY31RNIQACKELA41QTTRTAYGPN
51-10051GMNKMVINRL61EKLFVTNDAA71TILRELEVQH81PAAKMIVMAS91HMQEQEVGDG
101-150101TNFVLVFAGA111LLELAEELLR121IGLSVSEVIS131GYEIACKKAH141EILPELVCCS
151-200151AKNLRDVDEV161SSLLRTSIMS171KQYGSETFLA181KLIAQACVSI191FPDSGNFNVD
201-250201NIRVCKILGS211GIYSSSVLHG221MVFKKETEGD231VTSVKDAKIA241VYSCPFDGMI
251-300251TETKGTVLIK261TAEELMNFSK271GEENLMDAQV281KAIAGTGANV291IVTGGKVADI
301-350301ALHYANKYNI311MLVRLNSKWD321LRRLCKTVGA331TALPKLTPPV341QEEMGHCDSV
351-400351YLSEVGDTQV361VVFKHEKEDG371AISTIVLRGS381TDNLMDDIER391AVDDGVNTFK
401-450401VLTRDKRLVP411GGGATEIELA421KQITSYGETC431PGLEQYAIKK441FAEAFEAIPR
451-500451ALAENSGVKA461NEVISKLYSV471HQEGNKNVGL481DIEAEVPAVK491DMLEASILDT
501-548501YLGKYWAIKL511ATNAAVTVLR521VDQIIMAKPA531GGPKPPSGKK541DWDDDQND
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
36 GroEL-like equatorial domain superfamily Chaperonin TCP-1, conserved site - -
GPS-Palm: 0.87
Deep-Palm: 0.91
136 - - -
Deep-Palm: 0.95
148 -
Brain (34200797)
-
GPS-Palm: 0.86
Deep-Palm: 0.97
149 -
Brain (34200797)
-
GPS-Palm: 0.89
Deep-Palm: 0.97
187 - - -
GPS-Palm: 0.80
Deep-Palm: 0.69
205 - - -
GPS-Palm: 0.82
Deep-Palm: 0.41
244 SWISSPALM DBPTM CYSMODDB TCP-1/cpn60 chaperonin family
Liver (28526873)
Brain (35358180)
GPS-Palm: 0.85
Deep-Palm: 0.96
325 - - -
GPS-Palm: 0.91
Deep-Palm: 0.97
347 - - -
Deep-Palm: 0.89
430 - - -
GPS-Palm: 0.75
Deep-Palm: 0.91
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.455
5
Liver
Specificity: 0.250
5/5 (100.0%)
5
Brain
Specificity: 0.250
5/5 (100.0%)
1
Raw 264.7
Specificity: 0.050
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
9
Brain tissue (Mass)
Specificity: 0.450
9/56 (16.1%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine