Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P43155-2 | CRAT | Carnitine O-acetyltransferase (Carnitine acetylase) (EC … | Homo sapiens (Human) | 605 aa |
Protein Details: P43155-2 (CRAT)
Protein Information
| Accession | P43155-2 |
|---|---|
| Protein Names | Carnitine O-acetyltransferase (Carnitine acetylase) (EC 2.3.1.137) (EC 2.3.1.7) (Carnitine acetyltransferase) (CAT) (CrAT) |
| Gene Symbol | CRAT |
| Organism | Homo sapiens (Human) |
| Length | 605 aa |
| Isoforms | |
| Related PMIDs | 31251020 33636221 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MKASSRFKAH11QDALPRLPVP21PLQQSLDHYL31KALQPIVSEE41EWAHTKQLVD
51-10051EFQASGGVGE61RLQKGLERRA71RKTENWLSEW81WLKTAYLQYR91QPVVIYSSPG
101-150101VMLPKQDFVD111LQGQLRFAAK121LIEGVLDFKV131MIDNETLPVE141YLGGKPLCMN
151-200151QYYQILSSCR161VPGPKQDTVS171NFSKTKKPPT181HITVVHNYQF191FELDVYHSDG
201-250201TPLTADQIFV211QLEKIWNSSL221QTNKEPVGIL231TSNHRNSWAK241AYNTLIKDKV
251-300251NRDSVRSIQK261SIFTVCLDAT271MPRVSEDVYR281SHVAGQMLHG291GGSRLNSGNR
301-350301WFDKTLQFIV311AEDGSCGLVY321EHAAAEGPPI331VTLLDYVIEY341TKKPELVRSP
351-400351LVPLPMPKKL361RFNITPEIKS371DIEKAKQNLS381IMIQDLDITV391MVFHHFGKDF
401-450401PKSEKLSPDA411FIQMALQLAY421YRIYGQACAT431YESASLRMFH441LGRTDTIRSA
451-500451SMDSLTFVKA461MDDSSVTEHQ471KVELLRKAVQ481AHRGYTDRAI491RGEAFDRHLL
501-550501GLKLQAIEDL511VSMPDIFMDT521SYAIAMHFHL531STSQVPAKTD541CVMFFGPVVP
551-600551DGYGVCYNPM561EAHINFSLSA571YNSCAETNAA581RLAHYLEKAL591LDMRALLQSH
601-605601PRAKL
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 169 | - | - | - |
Deep-Palm: 0.80
|
|
| 180 | - | - | - |
Deep-Palm: 0.36
|
|
| 287 | - | - | - |
Deep-Palm: 0.87
|
|
| 337 | - | - | - |
Deep-Palm: 0.71
|
|
| 449 | - | - | - |
Deep-Palm: 0.80
|
|
| 562 | - | - | - |
Deep-Palm: 0.17
|
|
| 577 | - | - | - |
Deep-Palm: 0.16
|
|
| 595 | - | - | - |
Deep-Palm: 0.88
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.400
2
LNCaP
Specificity: 0.400
2/2 (100.0%)
2
cerebral cortex
Specificity: 0.400
2/2 (100.0%)
1
heart
Specificity: 0.200
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 27 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 277 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 277 | R → C | 0.003774 | SNP | Missense Mutation | UCEC |
| 301 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 321 | R → C | 0.002020 | SNP | Missense Mutation | PRAD |
| 602 | R → C | 0.002506 | SNP | Missense Mutation | COAD |