Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P43686-2 | PSMC4 | 26S proteasome regulatory subunit 6B … | Homo sapiens (Human) | 387 aa |
Protein Details: P43686-2 (PSMC4)
Protein Information
| Accession | P43686-2 |
|---|---|
| Protein Names | 26S proteasome regulatory subunit 6B (26S proteasome AAA-ATPase subunit RPT3) (MB67-interacting protein) (MIP224) (Proteasome 26S subunit ATPase 4) (Tat-binding protein 7) (TBP-7) |
| Gene Symbol | PSMC4 |
| Organism | Homo sapiens (Human) |
| Length | 387 aa |
| Isoforms | |
| Related PMIDs | 32944167 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MEEIGILVEK11AQDEIPALSV21SRPQTGLSFL31GPEPEDLEDL41YSRYKEEVKR
51-10051IQSIPLVIGQ61FLEAVDQNTA71IVGSTTGSNY81YVRILSTIDR91ELLKPNASVA
101-150101LHKHSNALVD111VLPPEADSSI121MMLTSDQKPD131VMYADIGGMD141IQKQEVREAV
151-200151ELPLTHFELY161KQIGIDPPRG171VLMYGPPGCG181KTMLAKAVAH191HTTAAFIRVV
201-250201GSEFVQKYLG211EGPRMVRDVF221RLAKENAPAI231IFIDEIDAIA241TKRFDAQTGA
251-300251DREVQRILLE261LLNQMDGFDQ271NVNVKVIMAT281NRADTLDPAL291LRPGRLDRKI
301-350301EFPLPDRRQK311RLIFSTITSK321MNLSEEVDLE331DYVARPDKIS341GADINSICQE
351-387351SGMLAVRENR361YIVLAKDFEK371AYKTVIKKDE381QEHEFYK
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 179 | - | - | - |
GPS-Palm: 0.95
|
|
| 210 | - | - | - |
Deep-Palm: 0.96
|
|
| 379 | - | - | - |
Deep-Palm: 0.92
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
PC3
Specificity: 1.000
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 108 | G → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 329 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 379 | C → C | 0.005618 | SNP | Silent | PAAD |