Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P45376 | Akr1b1 | Aldo-keto reductase family 1 member … | Mus musculus (Mouse) | 316 aa |
Protein Details: P45376 (Akr1b1)
Protein Information
| Accession | P45376 |
|---|---|
| Protein Names | Aldo-keto reductase family 1 member B1 (EC 1.1.1.21) (EC 1.1.1.300) (EC 1.1.1.372) (EC 1.1.1.54) (Aldehyde reductase) (Aldo-keto reductase family 1 member B3) (Aldose reductase) (AR) |
| Gene Symbol | Akr1b1 |
| Organism | Mus musculus (Mouse) |
| Length | 316 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 35358180 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MASHLELNNG11TKMPTLGLGT21WKSPPGQVTE31AVKVAIDLGY41RHIDCAQVYQ
51-10051NEKEVGVALQ61EKLKEQVVKR71QDLFIVSKLW81CTFHDKSMVK91GAFQKTLSDL
101-150101QLDYLDLYLI111HWPTGFKPGP121DYFPLDASGN131VIPSDTDFVD141TWTAMEQLVD
151-200151EGLVKTIGVS161NFNPLQIERI171LNKPGLKYKP181AVNQIECHPY191LTQEKLIEYC
201-250201HSKGIVVTAY211SPLGSPDRPW221AKPEDPSLLE231DPRIKAIAAK241YNKTTAQVLI
251-300251RFPIQRNLVV261IPKSVTPVRI271AENLKVFDFE281VSSEDMATLL291SYNRNWRVCA
301-316301LMSCAKHKDY311PFHAEV
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 45 | NADP-dependent oxidoreductase domain NADP-dependent oxidoreductase domain superfamily Aldo-keto reductase | - |
Brain
(35358180)
|
Deep-Palm: 0.87
|
|
| 81 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.43
|
|
| 187 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.56
|
|
| 200 | - | - |
Brain
(35358180)
|
GPS-Palm: 0.70
Deep-Palm: 0.77
|
|
| 299 | - | - |
NSC
(31772009)
|
GPS-Palm: 0.96
Deep-Palm: 0.28
|
|
| 304 | - | - | - |
GPS-Palm: 0.77
Deep-Palm: 0.04
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.600
3
Liver
Specificity: 0.150
3/3 (100.0%)
2
Brain
Specificity: 0.100
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
15
Brain tissue (Mass)
Specificity: 0.750
15/56 (26.8%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.