Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P46460 | Nsf | Vesicle-fusing ATPase (EC 3.6.4.6) (N-ethylmaleimide-sensitive … | Mus musculus (Mouse) | 744 aa |
Protein Details: P46460 (Nsf)
Protein Information
| Accession | P46460 |
|---|---|
| Protein Names | Vesicle-fusing ATPase (EC 3.6.4.6) (N-ethylmaleimide-sensitive fusion protein) (NEM-sensitive fusion protein) (Suppressor of K(+) transport growth defect 2) (Protein SKD2) (Vesicular-fusion protein NSF) |
| Gene Symbol | Nsf |
| Organism | Mus musculus (Mouse) |
| Length | 744 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 31311849 34200797 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAGRTMQAAR11CPTDELSLSN21CAVVNEKDFQ31SGQHVMVRTS41PNHKYIFTLR
51-10051THPSVVPGCI61AFSLPQRKWA71GLSIGQDIEV81ALYSFDKAKQ91CIGTMTIEID
101-150101FLQKKNIDSN111PYDTDKMAAE121FIQQFNNQAF131SVGQQLVFSF141NDKLFGLLVK
151-200151DIEAMDPSIL161KGEPASGKRQ171KIEVGLVVGN181SQVAFEKAEN191SSLNLIGKAK
201-250201TKENRQSIIN211PDWNFEKMGI221GGLDKEFSDI231FRRAFASRVF241PPEIVEQMGC
251-300251KHVKGILLYG261PPGCGKTLLA271RQIGKMLNAR281EPKVVNGPEI291LNKYVGESEA
301-350301NIRKLFADAE311EEQRRLGANS321GLHIIIFDEI331DAICKQRGSM341AGSTGVHDTV
351-400351VNQLLSKIDG361VEQLNNILVI371GMTNRPDLID381EALLRPGRLE391VKMEIGLPDE
401-450401KGRLQILHIH411TARMRGHQLL421SADVDIKELA431VETKNFSGAE441LEGLVRAAQS
451-500451TAMNRHIKAS461TKVEVDMEKA471ESLQVTRGDF481LASLENDIKP491AFGTNQEDYA
501-550501SYIMNGIIKW511GDPVTRVLDD521GELLVQQTKN531SDRTPLVSVL541LEGPPHSGKT
551-600551ALAAKIAEES561NFPFIKICSP571DKMIGFSETA581KCQAMKKIFD591DAYKSQLSCV
601-650601VVDDIERLLD611YVPIGPRFSN621LVLQALLVLL631KKAPPQGRKL641LIIGTTSRKD
651-700651VLQEMEMLNA661FSTTIHVPNI671ATGEQLLEAL681ELLGNFKDKE691RTTIAQQVKG
701-744701KKVWIGIKKL711LMLIEMSLQM721DPEYRVRKFL731ALMREEGASP741LDFD
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 11 | Aspartate decarboxylase-like domain superfamily |
Brain
(34200797)
|
Brain
(35358180)
Brain
(31311849)
|
GPS-Palm: 0.65
Deep-Palm: 0.04
|
|
| 21 | Aspartate decarboxylase-like domain superfamily |
Brain
(34200797)
|
Brain
(35358180)
|
Deep-Palm: 0.60
|
|
| 59 | SWISSPALM DBPTM CYSMODDB | Cell division protein 48 (CDC48), N-terminal domain |
Forebrain
(28680068)
|
Brain
(35358180)
Brain
(31311849)
|
GPS-Palm: 0.90
Deep-Palm: 0.88
|
| 91 | - | - | - |
GPS-Palm: 0.73
Deep-Palm: 0.71
|
|
| 250 | ATPase family associated with various cellular activities (AAA) |
brain
(39008777)
|
Brain
(35358180)
|
GPS-Palm: 0.69
Deep-Palm: 0.96
|
|
| 264 | ATPase family associated with various cellular activities (AAA) |
Brain
(31311849)
brain
(39008777)
|
Brain
(35358180)
Brain
(31311849)
|
GPS-Palm: 0.93
Deep-Palm: 0.97
|
|
| 334 | ATPase family associated with various cellular activities (AAA) |
Brain
(34200797)
|
Brain
(31311849)
|
Deep-Palm: 0.56
|
|
| 568 | ATPase family associated with various cellular activities (AAA) |
Brain
(34200797)
|
Brain
(31311849)
|
GPS-Palm: 0.72
Deep-Palm: 0.73
|
|
| 582 | - | - | - |
GPS-Palm: 0.81
Deep-Palm: 0.27
|
|
| 599 | - |
Brain
(31311849)
|
Brain
(35358180)
Brain
(31311849)
|
GPS-Palm: 0.67
Deep-Palm: 0.85
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.455
5
Brain
Specificity: 0.111
5/5 (100.0%)
4
Liver
Specificity: 0.089
4/4 (100.0%)
2
Testis
Specificity: 0.044
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
34
Brain tissue (Mass)
Specificity: 0.756
34/56 (60.7%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.