Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P46782 | RPS5 | Small ribosomal subunit protein uS7 … | Homo sapiens (Human) | 204 aa |
Protein Details: P46782 (RPS5)
Protein Information
| Accession | P46782 |
|---|---|
| Protein Names | Small ribosomal subunit protein uS7 (40S ribosomal protein S5) [Cleaved into: Small ribosomal subunit protein uS7, N-terminally processed (40S ribosomal protein S5, N-terminally processed)] |
| Gene Symbol | RPS5 |
| Organism | Homo sapiens (Human) |
| Length | 204 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19137006 29733200 31251020 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MTEWETAAPA11VAETPDIKLF21GKWSTDDVQI31NDISLQDYIA41VKEKYAKYLP
51-10051HSAGRYAAKR61FRKAQCPIVE71RLTNSMMMHG81RNNGKKLMTV91RIVKHAFEII
101-150101HLLTGENPLQ111VLVNAIINSG121PREDSTRIGR131AGTVRRQAVD141VSPLRRVNQA
151-200151IWLLCTGARE161AAFRNIKTIA171ECLADELINA181AKGSSNSYAI191KKKDELERVA
201-204201KSNR
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 66 | SWISSPALM DBPTM CYSMODDB | - |
HeLa
(37611173)
| - |
GPS-Palm: 0.96
Deep-Palm: 0.78
|
| 155 | - |
HeLa
(37611173)
|
cerebral cortex
(36430497)
Unknown
(32651440)
|
GPS-Palm: 0.95
Deep-Palm: 0.96
|
|
| 172 | SWISSPALM DBPTM CYSMODDB | Ribosomal protein S7p/S5e |
SW480 cell line
(26865113)
|
cerebral cortex
(36430497)
LNCaP
(31251020)
Unknown
(32651440)
|
GPS-Palm: 0.94
Deep-Palm: 0.96
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.300
3
LNCaP
Specificity: 0.231
3/3 (100.0%)
2
HAP1 cell
Specificity: 0.154
2/2 (100.0%)
2
Jurkat T cell
Specificity: 0.154
2/2 (100.0%)
2
cerebral cortex
Specificity: 0.154
2/2 (100.0%)
1
293T cell
Specificity: 0.077
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
Cerebral Cortex (Mass)
Specificity: 0.231
3/4 (75.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 91 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 155 | C → R | 0.002033 | SNP | Missense Mutation | LUSC |
| 172 | C → C | 0.002506 | SNP | Silent | COAD |
| 188 | Y → C | 0.002506 | SNP | Missense Mutation | COAD |