Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P47738 Aldh2 Aldehyde dehydrogenase, mitochondrial (EC 1.2.1.3) … Mus musculus (Mouse) 519 aa

Protein Details: P47738 (Aldh2)

Protein Information
AccessionP47738
Protein NamesAldehyde dehydrogenase, mitochondrial (EC 1.2.1.3) (AHD-M1) (ALDH class 2) (ALDH-E2) (ALDHI)
Gene SymbolAldh2
OrganismMus musculus (Mouse)
Length519 aa
IsoformsNo isoforms
Related PMIDs 28526873 29575903 29733200 34200797 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MLRAALTTVR11RGPRLSRLLS21AAATSAVPAP31NHQPEVFCNQ41IFINNEWHDA
51-10051VSRKTFPTVN61PSTGEVICQV71AEGNKEDVDK81AVKAARAAFQ91LGSPWRRMDA
101-150101SDRGRLLYRL111ADLIERDRTY121LAALETLDNG131KPYVISYLVD141LDMVLKCLRY
151-200151YAGWADKYHG161KTIPIDGDFF171SYTRHEPVGV181CGQIIPWNFP191LLMQAWKLGP
201-250201ALATGNVVVM211KVAEQTPLTA221LYVANLIKEA231GFPPGVVNIV241PGFGPTAGAA
251-300251IASHEGVDKV261AFTGSTEVGH271LIQVAAGSSN281LKRVTLELGG291KSPNIIMSDA
301-350301DMDWAVEQAH311FALFFNQGQC321CCAGSRTFVQ331ENVYDEFVER341SVARAKSRVV
351-400351GNPFDSRTEQ361GPQVDETQFK371KILGYIKSGQ381QEGAKLLCGG391GAAADRGYFI
401-450401QPTVFGDVKD411GMTIAKEEIF421GPVMQILKFK431TIEEVVGRAN441DSKYGLAAAV
451-500451FTKDLDKANY461LSQALQAGTV471WINCYDVFGA481QSPFGGYKMS491GSGRELGEYG
501-519501LQAYTEVKTV511TVKVPQKNS
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
38 Aldehyde dehydrogenase, N-terminal - -
Deep-Palm: 0.03
68 SWISSPALM DBPTM CYSMODDB Aldehyde dehydrogenase family
Liver (28526873)
Brain (35358180)
Deep-Palm: 0.98
147 - - -
GPS-Palm: 0.73
Deep-Palm: 0.64
181 SWISSPALM DBPTM CYSMODDB Aldehyde dehydrogenase family
Liver (28526873)
-
GPS-Palm: 0.67
Deep-Palm: 0.32
320 - - -
GPS-Palm: 0.79
Deep-Palm: 0.22
321 - - -
GPS-Palm: 0.92
Deep-Palm: 0.17
322 - - -
GPS-Palm: 0.83
Deep-Palm: 0.40
388 SWISSPALM DBPTM CYSMODDB Aldehyde dehydrogenase family
liver (26165157)
MLE (39008777)
Liver (28526873)
Liver (37925639)
Brain (35358180)
GPS-Palm: 0.91
Deep-Palm: 0.97
474 - - -
Deep-Palm: 0.76
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.385
5
Liver
Specificity: 0.135
5/5 (100.0%)
4
Brain
Specificity: 0.108
4/4 (100.0%)
2
Raw 264.7
Specificity: 0.054
2/2 (100.0%)
2
Testis
Specificity: 0.054
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.875
21
Brain tissue (Mass)
Specificity: 0.568
21/56 (37.5%)
3
Liver tissue (Mass)
Specificity: 0.081
3/8 (37.5%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine