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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P47879 Igfbp4 Insulin-like growth factor-binding protein 4 … Mus musculus (Mouse) 254 aa

Protein Details: P47879 (Igfbp4)

Protein Information
AccessionP47879
Protein NamesInsulin-like growth factor-binding protein 4 (IBP-4) (IGF-binding protein 4) (IGFBP-4)
Gene SymbolIgfbp4
OrganismMus musculus (Mouse)
Length254 aa
IsoformsNo isoforms
Related PMIDs 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MLPFGLVAAL11LLAAGPRPSL21GDEAIHCPPC31SEEKLARCRP41PVGCEELVRE
51-10051PGCGCCATCA61LGLGMPCGVY71TPRCGSGMRC81YPPRGVEKPL91RTLMHGQGVC
101-150101TELSEIEAIQ111ESLQTSDKDE121SEHPNNSFNP131CSAHDHRCLQ141KHMAKIRDRS
151-200151KMKIVGTPRE161EPRPVPQGSC171QSELHRALER181LAASQSRTHE191DLFIIPIPNC
201-250201DRNGNFHPKQ211CHPALDGQRG221KCWCVDRKTG231VKLPGGLEPK241GELDCHQLAD
251-254251SFQE
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
27 Insulin-like growth factor-binding protein, IGFBP - -
Deep-Palm: 0.82
30 Insulin-like growth factor-binding protein, IGFBP INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN - -
Deep-Palm: 0.66
38 Insulin-like growth factor-binding protein, IGFBP Growth factor receptor cysteine-rich domain superfamily INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN - -
Deep-Palm: 0.71
44 Insulin-like growth factor-binding protein, IGFBP Growth factor receptor cysteine-rich domain superfamily Insulin-like growth factor binding protein, N-terminal, Cys-rich conserved site INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN - -
Deep-Palm: 0.39
53 - - -
Deep-Palm: 0.57
55 - - -
GPS-Palm: 0.85
Deep-Palm: 0.50
56 - - -
GPS-Palm: 0.77
Deep-Palm: 0.40
59 - - -
Deep-Palm: 0.26
67 - - -
Deep-Palm: 0.13
74 - - -
Deep-Palm: 0.60
80 - - -
Deep-Palm: 0.54
100 - - -
Deep-Palm: 0.95
131 - - -
Deep-Palm: 0.03
138 - - -
Deep-Palm: 0.05
170 SWISSPALM DBPTM CYSMODDB -
liver (26165157)
Liver (34884899)
Brain (35358180)
Deep-Palm: 0.98
200 - - -
GPS-Palm: 0.81
Deep-Palm: 0.04
211 - - -
Deep-Palm: 0.04
222 - - -
Deep-Palm: 0.83
224 - - -
GPS-Palm: 0.66
Deep-Palm: 0.92
245 - - -
Deep-Palm: 0.18
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
Liver
Specificity: 0.111
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.625
5
Brain tissue (Mass)
Specificity: 0.556
5/56 (8.9%)
3
Liver tissue (Mass)
Specificity: 0.333
3/8 (37.5%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine